Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours Max Marks: 40
Date: 04-03-2021
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Instructions:1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
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5. Write legibly.Section 1
1.Multiple choice question : (10)
a) A receptor which itself has enzyMatic
Property is(A) Insulin receptor (B) Progesterone
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receptor (C) Thyroxine receptor (D) Glucagonreceptor
b) Drug cumulation is the basis of organ toxicity
of the following drug when used for prolong
periods:(A) Prednisolone (B)chioroquine (C)
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Aspirin (D) Hydralazinec) A suspected case of poisoning has been
brought to the casualty with weakness, fainting,
involuntory passage of urine and stools, profuse
sweating, salivation, watering
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from nose and eyes. His pulse is 120/min, lowvolume, BP 90/60 mm Hg, respiration shallow,
pupil constricted, muscles flabby with
occasional fasciculations. Which is the
most likely type of poisoning? (A) Belladona (B)
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Barbiturate (C) Anticholinesterase(D)Paracetamol
d) Select the antihistaminic which modulates
calcium channels and has prominent
labyrinthine suppressant property: (A)
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Cyproheptadine (B) Cinnarizine (C) Clemastine(D)
Cetirizine
e) The following drug is used for cervical
priming to facilitate labour:(A) Oxytocin (B)
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Clomiphene (C) Progesterone (D) ProstaglandinE2
f) The local anaesthetic with the longest
duration of action is:(A) Procaime(B)
Chloroprocaine (C) Lignocaine (D) Dibucaine
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g) Select the drug that antagonises diazepamaction non-competitively: (A) Adenosine (B)
Flumazenil (C) Bicuculline (D) Valproic acid
h) Which of the following drugs is a potassium
channel opener: (A) Nicorandil (B) Hydralazine
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(C) Glibenclamide (D) Amiloridei) The following antihypertensive combination is
irrational, and therefore should not be used: (A)
Nifedipine + hydralazine (B) Amlodipine +
atenolol (C) Enalapril + clonidine
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(D) Enalapril + hydrochlorothiazidej) Thiazide diuretics and furosemide have
directionally opposite effect on the net renal
excretion of the following substance: (A) Uric
acid (B) Calcium (C) Magnesium (D)
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BicarbonateSection 2
2.Write short notes on: (two out of three) (10)
a) Pharmacotherapy of Peptic Ulcer.
b) Pharmacotherapy of Migraine.
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c) Pharmacotherapy of Rheumatoid Arthritis.3.Write briefly on: (Four out of five) (10)
a) Names of SSRI
b) ORS
c) Pheochromocytoma.
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d) Zero order kinetics.e) Idiosyncratic drug reactions
4.Write short notes on: (Two out of three) (10)
a) Adverse drug reactions of antipsychotic
medication.
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b) Myocardial Infarction.c) Status Epilepticus.
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