Download MBBS (Bachelor of Medicine and Bachelor of Surgery) Latest MUHS Pharmacology Question Bank
Pharmacology MUHS Questions
(2005-2015)
Paper II
Endocrine
SAQs
1. Oral Antidiabetics (Classify,Example, MoA, ADR ? Metformin; Acarbose ? MoA,
ADR;Tolbutamine +Oxyphen butazone-basis of giddiness,sweating,tremors in NIDDM )
2. Oxytocin/(Ergometrin or PG analogues)(Uterine stimulants - Classify, Indications, RoA, Contra.)
3. Topical Steroids(Name, MoA)
4. Contraceptives(Classify, Emergency Regimens, Combination Pills ? MoA, Adv, Contra;
Mifepristone ? MoA, TU)
5. Anti-Thyroid drugs(Classify, in lactation)
6. Radioactive Iodine(Advantages & Disadvantages)
7. Lugol's Iodine(Use in Hyperthyroidism)
8. Ovulation Inducers(Enumerate, ADR, Common Problems Encountered; Clomiphene citrate-
Indications, ADR)
9. Tocolytics (Name, ADR)
10. Naturally Occuring Progesterone(Why not used? Alternatives)
11. Estrogen Receptor Modulator(TU, ADR)
LAQ's
1. Corticosteroids(Glucocorticoids - Classify, ADR, TU, Precautions)
2. Oral Antidiabetics(Classify, Obese, Sulfonyureas - MoA, ADR; Thiazolidinediones ? MoA, Actions,
ADR; Management of newly diagnosed case, Any two FDC's with Advantages)
3. Insulin(Sources, Human/Conventional, Indications, ADR, Prevention of ADR)
4. Anti-Thyroid(Classify, MoA, ADR, Carbimazole - TU, ADR; Radioactive Iodine ? MoA, ADR)
5. Contraceptives(Classify, Preparations, Comination pill ? MoA, Toxicity)
Chemotherapy
SAQ's
1. Artesunate(ACT ? Indication, Adv, Regimen; Artemisinin ? MoA, TU, ADR)
2. Beta Lactams(Penicillinase Inhibitors; Augmentin; Antibiotic Resistance to Penicillins)
3. Anti-Malarial(Classify, Chloroquine ? TU, not used in intestinal amoebiasis, resistant malaria;
Quinine)
4. Cephalosporins(Classify, Third Gen; 3rd/4th; Penicillin/Cephalosporin, Typhoid Fever)
5. Fluoroquinolones(Classify, Newer FQ's; Nalidixic/Ciprofloxacin; ADR; FQ's Eliminated by hepatic
and rectal route;)
6. Metronidazole(ADR, TU)
7. Cotrimaxazole(MoA, TU; Sequential Blockade ? Two examples)
8. Chemoprophylaxis(Rhematic Fever)
9. Anti-Tubercular(DOTS; MDR-TB; Pyridoxine+INH; Typhoid Carriers;
10. Aminoglycosides(Common Features, Streptomycin ? TU)
11. Anti-Leprotic(Multibacillary Leprosy ? Why Multidrug?; Lepra reaction ? Cause, Types, Drugs;)
12. Anti-Helminthic(Mebendazole; Praziquantel/Niclosamide in T.solium; Vermifuge/Vermicide[with
MoA and Examples]; Albendazole/Mebendazole; Mixed Roundworm Infestation, MoA)
13. Vaginal Discharge(Drug of Choice, Microbial Causes)
14. Macrolides(Enumerate; Azithromycin ? Adv, TU, Spectrum, PKS,Tolerability, Interactions)
15. Urinary Antiseptics(Definition, Examples)
16. Sulfonamide(Sulfaslazine ? TU, Burns)
17. Anti-Virals(NRTI's)
18. Tetracyclins(Doxycyclin ? Adv)
LAQ's
1. Cephalosporins(Classify, MoA, ADR, TU; 3rd/1st )
2. Aminoglycosides(Classify, MoA, Streptomycin - ADR, TU)
3. Penicillin(Classify, MoA, Ampicillin&Amoxycillin - ADR, TU; PenicillinG ? MoA, ADR,TU)
4. Selection of Antibiotic
5. Anti-Tubercular(Classify, ADR, Rifampicin ? PKS, ADR, Spectrum, TU, Action; INH ? MoA, ADR;
Causes of failure of drug treatment; MDR-TB Treatment; DOTS; RNTCP)
6. FQ's(Classify, 1st/2nd [Spectrum, Adv, ADR,Indications])
7. Anti-Malarial(Classify, Chloroquine ? MoA, TU; Site of Action)
8. Antibiotic Resistance(Mechanisms and How to Overcome/Prevent)
9. Anti-Amoebic(Classify, Intestinal Amoebiasis, ADR)
10. Anti-Leprotic(Multibacillary, ENL, Lepra Reaction)
11. Cotrimoxazole(MoA, TU, ADR)
CNS
SAQ's
1. Opioids (Antagonists-Classify, TU;Morphine-TU, Poisoning, Contra. of Morphine in head injury)
2. Preanaesthetic medication(Purpose of each drug, Route of administration, Dose)
3. Antiparkinsonian drugs(Levodopa, Levodopa+ carbidopa, Amantadine, L-dopa+multivitamin
consequences, Drug of choice with reason)
4. NSAIDs(ADR, Aspirin-MoA as antinflammatory, antiplatelet)
5. Anaesthetics (Lignocaine, Desired & undesired properties of IV gen anaesthetic agents, Use of
thiopentone sodium and NO in Gen. Anaesthesia)
6. Antiepileptics(Use of Diazepam in status epilepticus, Carbamazepine, Drug used in both types of
epilepsy-ADR ;Pregnancy-problems encountered, precautions and actions to avoid them)
7. Benzodiazepines/Barbiturates
8. Antianxiety drugs(MoA)
9. Barbiturates(Classification, Phenobarbitone-TU; Poisoning- basis of forced alkaline diuresis)
10. Benzodiazepines(Zaleplon/Diazepam, Diazepam-TU)
11. Alcohol(4 methyl pyrazole in methyl alcohol poisoning, Disulfiram + ethyl alcohol, Methanol
poisoning)
12. Antidepressants(TCA-ADR, Cheese reaction of MAO inhibitors, Serotonin reuptake inhibitors)
LAQ's
1. Sedative & Hypnotics(Classify;Benzodiazeoines-MoA,TU, Adv over barbiturates; Management of
insomnia)
2. Antidepressants(Classify, SSRIs-ADR,TU; Pharmacology of TCAs)
3. Antiepileptics (Phenytoin sodium-MoA,TU,ADR; Carbamazepine- MoA,TU,ADR; Drugs used in
Grandmal & Petitmal epilepsy, Status epilepticus)
4. NSAIDs(Classify, MoA; Aspirin-MoA,TU,ADR,Contra;COX-2 inhibitors-ADRs;Adv and disadv of
selectiveNSAIDs)
5. Alcohol(Drug dependence,Management of Chronic alcoholism)
6. Opium ( Enumerate alkaloids, Morphine- MoA,TU,ADR,)
7. Opioid/Non-opioid analgesics(Uses,Drug of choice with dose schedule,ADRs,Contra)
8. Antiparkinsonian drugs(Classify; Levodopa+Carbidopa-Adv and Disadv ; Levodopa- MoA,TU,ADR)
9. Antianxiety drugs(Classify, Diazepam- MoA,TU,ADR,Contra)
10. Preanaesthetics(Enumarate, Basis of each , Disadv )
Miscellaneous-
SAQ's
1. Bronchial asthama-(Classify,ADRs; Selective Beta 2 agonist- MoA, ADR; Aminophylline- MoA,
ADR; Budesonide- MoA, ADR ; Inhalational corticosteroids- Enumerate, MoA, ADR; Non
autonomic drug groups- Enumerate, MoA)
2. Migraine(Prophylaxis; Sumatriptan- MoA, ADR)
3. Cough(Classify,MoA ; Antitussive agents-MoA, non-opioid antitussives [Enumerate,TU];
Bromhexine-mode,dose)
4. Gout(Enumerate drugs,MoA;)
5. Antihistaminics(Classify, Uses;H1 antagonists-TU,ADR; Non sedative antihistaminics-Adv,
Indications)
6. Rheumatoid arthritis(Treatment,Methotrexate-MoA,TU)
7. Scabies(Enumerate, Merits and demerits of each)
8. Vaccines(Defn,Viral vaccines examples, Passive immunization, infective diseases treated with
passive immunization)
9. Immunosupressants(Classify, MoA, TU, ADR; Cyclosporine ? TU, ADR)
LAQ's
1. NMJ blocking drugs(Classify,Peripherally acting-drug interactions,TU)
2. H1 receptor antagonists(Clinical classification;Older H1 blockers-TU,ADR; Newer-Adv,Disadv)
This post was last modified on 30 November 2021