Download MBBS 2nd Year 2022 August 526062 Pharmacology II Mcqs MCQs Question Paper

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THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[MBBS 0822] AUGUST 2022 Sub. Code :6062

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M.B.B.S. DEGREE EXAMINATION

(For the candidates admitted from the Academic Year 2019-2020)

SECOND YEAR - SUPPLEMENTARY (CBME)

PAPER II - PHARMACOLOGY II

O.P. Code: 526062

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Time: 30 Minutes Maximum : 20 Marks

Answer All Questions

Choose one correct answer in the box provided in the Answer Script.

No overwriting should be done.

I. Multiple Choice Questions: (20x1=20)

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1. A patient has subclinical folate deficiency. All of the following drugs can precipitate megaloblastic anemia in this patient except:
   1. Alcohol
   2. Phenytoin
   3. Chloroquine
   4. Sulfasalazine

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2. Indication for intramuscular iron therapy is
   1. Pregnancy
   2. Postpartum period
   3. Emergency surgery
   4. Oral iron intolerance

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3. Which of the following drugs does not act by blocking GpIIb/IIIa receptors?
   1. Abciximab
   2. Eptifibatide
   3. Tirofiban
   4. Clopidogrel

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4. Recent oral direct thrombin inhibitor which can be used for prevention of stroke is
   1. Dabigatran
   2. Ximelagatran
   3. Lepirudin
   4. Saxagliptin

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5. A 30 year old pregnant woman develops tuberculosis. Which of the following antitubercular drugs should not be used?
   1. INH
   2. Rifampicin
   3. Streptomycin
   4. Ethambutol

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6. Which of the following can be given orally?
   1. Cytosine arabinoside
   2. Cisplatin
   3. Doxorubicin
   4. Mesna

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7. Which of the following anticancer drugs can cross blood brain barrier?
   1. Cisplatin
   2. Nitrosourea
   3. Vincristine
   4. Vinblastine

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8. Which of the following parameters is not monitored in a patient on methotrexate therapy?
   1. Liver function tests
   2. Lung function tests
   3. Eye examination
   4. Haemogram

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9. A patient receiving allopurinol requires dose reduction of:
   1. 6-Mercaptopurine
   2. Cyclophosphamide
   3. 6-Thioguanine
   4. Cimetidine

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10. About vinca alkaloids, true is:
    1. Inhibits mitotic spindle
    2. Enhances polymerization of tubulin
    3. Inhibits topoisomerase 1
    4. Inhibits topoisomerase II

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11. Which of the following is given at intervals as a pulsatile therapy?
    1. GnRH
    2. GH
    3. FSH
    4. Estrogen

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12. Conversion of T₄ to T₃ is inhibited by all except:
    1. Propanolol
    2. Propylthiouracil
    3. Amiodarone
    4. Methimazole

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13. All of the following preparations of insulin are rapid and short acting except:
    1. Lispro
    2. Aspart
    3. Glargine
    4. NPH

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14. The following statements regarding finasteride are true except:
    1. It is used in the treatment of benign prostatic hyperplasia
    2. Impotence is well documented after its use
    3. It blocks the conversion of dihydrotestosterone to testosterone
    4. It is a 5 a reductase inhibitor

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15. Which of the following progesterone is used in emergency contraception?
    1. Levonorgestrel
    2. Micronised Progesterone
    3. Norgesterone
    4. Depot Medroxyprogesterone acetate

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16. Which of the following agents is beneficial in NSAID induced gastric ulcer?
    1. PGE₁ agonist
    2. PGE₂ agonist
    3. PGD₂ agonist
    4. PGF_2a agonist

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17. Drug of choice for treatment of malaria due to P. vivax in a 25 year old pregnant female is:
    1. Chloroquine
    2. Primaquine
    3. Sulfadoxine-pyrimethamine
    4. Quinine

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18. Drug of choice for bacterial vaginosis is:
    1. Metronidazole
    2. Ampicillin
    3. Ciprofloxacin
    4. Fluconazole

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19. Albendazole is effective against all of the following except:
    1. Roundworm
    2. Hookworm
    3. Tapeworm
    4. Pinworm

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20. Commonest side effect of Dapsone is:
    1. Hemolytic anemia
    2. Thrombocytopenia
    3. Cyanosis
    4. Bone marrow depression

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[MBBS 0822]

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