Download MBBS 2nd Year 2023 July 526063 Pathology I Mcqs MCQs Question Paper

FirstRanker.com

A Firstranker's choice

THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

--- Content provided by​ FirstRanker.com ---

[MBBS 0723] JULY 2023 Sub. Code : 6063

M.B.B.S. DEGREE EXAMINATION

(For the candidates admitted from the Academic Year 2019-2020)

SECOND YEAR - (CBME)

PAPER III - PATHOLOGY -1

--- Content provided by‍ FirstRanker.com ---

Q.P. Code: 526063

Time: 30 Minutes Maximum : 20 Marks

Answer All Questions

Choose one correct answer in the box provided in the Answer Script. No overwriting should be done. Choice should be given in Capital Letters.

II1. Multiple Choice Questions: (20x1=20)

--- Content provided by‍ FirstRanker.com ---

1. The chief protein component of intrinsic defect seen in Hereditary Spherocytosis is
   A) Ubiquitin B) Spectrin C) Tropomyosin D) Actin
2. The type mutations involved in beta thalassemia is
   A) Driver mutation B) Transgenic mutation
   C) Splicing mutation D) Reverse mutation

--- Content provided by​ FirstRanker.com ---

3. PIGA gene is acquired in PNH as
   A) X linked B) Autosomal Dominant
   C) Autosomal Recessive D) Y linked
4. Tay Sach’s disease caused by inability to metabolise
   A) Glucokinase B) Fructokinase
   

   --- Content provided by⁠ FirstRanker.com ---

   C) Gmagangliosides D) Gmsgangliosides
5. Klinefelter’s syndrome shows elevated levels of
   A) Testosterone B) FSH C) LH D) Estrogen
6. Turner’s syndrome carry the risk of development of the following tumour
   A) Neuroblastoma B) Hepatoblastoma
   

   --- Content provided by​ FirstRanker.com ---

   C) Gonadoblastoma D) Ganglioneuroma
7. The most effective Antigen presenting cells(APCs) are
   A) Dendritic cells B) Neutrophils C) Lymphocytes D) NK cells
8. The mediators produced by the Mast cells are responsible for
   A) Type I hypersensitivity B) Type II hypersensitivity
   

   --- Content provided by​ FirstRanker.com ---

   C) Type III hypersensitivity D) Type IV hypersensitivity
9. Among the genes known to be associated with autoimmunity, the greatest contribution is from
   A) HLA gene
10. Smith antigen (Sm) is associated with
    A) Sjogren syndrome B) Rheumatoid arthritis
    

    --- Content provided by‌ FirstRanker.com ---

    C) Systemic sclerosis D) SLE
11. Acute cellullar rejection involves killing of cells by
    A) CD 2+ B) CD 3+ C) CD 8+ D) CD 10+
12. HHV 8 genome is found in the following cell of infected subjects
    A) T- cell B) B-cell C) Neutrophil D) Monocyte

--- Content provided by FirstRanker.com ---

13. Driver mutations are
    A) Loss of function B) Passenger mutations
    C) Initiating mutations D) Repeat mutations
14. The governor of the cell cycle is
    A) BRAF gene B) CDK4 gene C) Cyclin D gene D) RB gene

--- Content provided by FirstRanker.com ---

15. Warburg effect is
    A) Anerobic glycolysis B) Aerobic glycolysis
    C) Oxidative phosphorylation D) gluconeogenesis
16. Acute promyelocytic Leukemia is a reciprocal translocation between chromosome 15 and 17 causing a fusion gene
    A) BCR-ABL B) C-myc IGH C) PML-RARa D) FLI-EWSR

--- Content provided by⁠ FirstRanker.com ---

17. Polio virus infects human cells by binding to
    A) CD4 B) CD8 C) CD117 D) CD155
18. A low CD4 count before starting ART is an important risk factor for the development of
    A) Leprosy B) Tuberculosis C) Mucor D) Aspergillosis
19. The fat burning molecule is
    

    --- Content provided by⁠ FirstRanker.com ---

    A) Ghrelin B) Insulin C) Adiponectin D) Leptin
20. The chromosomal anomalies associated with fetal hydrops is
    A) 45X B) 47XXY C) Trisomy 13 D) Trisomy 22.

[MBBS 0723]

FirstRanker.com

--- Content provided by⁠ FirstRanker.com ---