[MBBS 0223] FEBRUARY 2023 Sub. Code :6065
M.B.B.S. DEGREE EXAMINATION
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(For the candidates admitted from the Academic Year 2019-2020)
SECOND YEAR - (CBME)
PAPER III - MICROBIOLOGY -1
O.P. Code: 526065
Time: Three hours Maximum : 100 Marks (80 Theory + 20MCQs)
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Answer all the Questions
I. Essay: 2x15=30
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A 60 year old diabetic patient was admitted in surgery ward with c/o blackish discolouration of Right foot 2 days after a road traffic injury. O/E there is foul smelling discharge and crepitus in the wound site. Microscopic examination of discharge reveal Gram positive bacilli. Answer the following questions :
- Enumerate the organisms that are causing the symptoms.
- Write the pathogenesis and clinical manifestation of the organism.
- Explain the diagnostic methods.
- Mention the management.
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Write the classification of Disinfectants depending upon its efficacy. Explain in detail about intermediate level of Disinfectant.
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II. Write Short notes on: (10 x5=50)
- Write the lab diagnosis of cutaneous infection caused by dermatophytes.
- Explain the working mechanism of Fluorescence microscope.
- Write Short notes on Automated Blood culture techniques.
- Define genetic engineering and write the procedure and application of recombinant DNA technique.
- Write a Short note on Humoral Immunodeficiency Diseases.
- Write the method of production of Monoclonal antibody and its application.
- Describe the wound class type in Surgical Site Infection and its prevention.
- Write the preventive measures for Measles.
- Explain the pathogenesis and lab diagnosis of Mycetoma foot
- Write short notes on congenital Rubella Syndrome.
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