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[MBBS 0723] JULY 2023 Sub. Code :6063
M.B.B.S. DEGREE EXAMINATION
(For the candidates admitted from the Academic Year 2019-2020)
SECOND YEAR - (CBME)
PAPER III - PATHOLOGY -1
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O.P. Code: 526063
Time: Three hours Maximum : 100 Marks (80 Theory +20MCQs)
Answer all the Questions
I. Essay: (2x15=30)
-
30/Male presented with massive splenomegaly his total count was 2,35,000 cells per mm’ with preponderance of Neutrophilic precursors. Platelet count was 1,80,000 cells per mm’.
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- What is your diagnosis?
- What is the molecular basis of this disease?
- Write about the morphological features in this condition. Classify myeloproliferative neoplasms.
-
25 years female presented with malar rash on the face, fever, painful joints of fingers.
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- What is your diagnosis?
- Write about the pathogenesis and diagnosis of the disease.
II. Write Short notes on: (10 x 5 = 50)
- 20 years female was diagnosed as extrapulmonary tuberculosis. She is very upset with the diagnosis. How will you support and educate her?
- Disorders of pigments.
- What is the role of prostaglandins in inflammation?
- What is cross matching? Types of cross matching and its importance.
- What are the types of carcinogens? Write about microbial carcinogens.
- What do you know about stem cells? What is the role of stem cells in diseases?
- Von Willebrand disease.
- 30 years female presented with menorrhagia. She has pallor, koilonychia. What will be the hematological findings in this patient?
- What are the investigations required in a case of bleeding disorder?
- 3 years male child had frontal bossing, pigeon chest, bowing of legs. What are the metabolic changes due to Vitamin D deficiency? If seen in adults what is the clinical manifestation?
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