DNB 2020 Dec Previous Question Papers-(Diplomate of National Board) Under NBE
BIOCHEMISTRY
PAPER-IV
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BCHEM/D/20/03/IV
Time: 3 hours
Max. Marks: 100
Important Instructions:
- You are provided with 5 answer sheet booklets. Each individual answer sheet booklet consists of 10 pages excluding the covering jackets.
- Answers to all the questions must be attempted within these 5 answer sheet booklets which must be later tagged together at the end of the exam.
- No additional supplementary answer sheet booklet will be provided.
- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts wherever appropriate.
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Write short notes on:
- Technique of development of transgenic animals and their uses in medical research. 10
- Techniques involved in proteomic studies. 10
- Gut microbiome, prebiotics and probiotics. 10
- a) Glucagon-like peptide -1 and its analogues
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b) Anti-GAD antibody. 5+5 - Techniques for determination of primary and quaternary structure of proteins. 10
- Reverse transcriptase-polymerase chain reaction (RT-PCR) and antigen testing in COVID-19 diagnosis. 10
- Laboratory tests for thyroid function evaluation and role of anti-TPO antibodies in diagnosis of thyroid disorders. 10
- Techniques of HLA typing & matching and disease association with different HLA types. 10
- Impact factor of a journal and H-index of an author. 10
- a) CRISPR system in genetic engineering.
b) Calculation of sample size in animal studies. 5+5
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