Download Diplomate of National Board (DNB) 2020 December BIochemIstry Paper IV Question Paper
NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2020
BIOCHEMISTRY
PAPER-IV
Time: 3 hours
BCHEM/D/20/03/IV
Max. Marks:100
Important Instructions:
You are provided with 5 answer sheet booklets. Each individual answer sheet booklet consists
of 10 pages excluding the covering jackets.
Answers to all the questions must be attempted within these 5 answer sheet booklets which
must be later tagged together at the end of the exam.
No additional supplementary answer sheet booklet will be provided.
Attempt all questions in order.
Each question carries 10 marks.
Read the question carefully and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Technique of development of transgenic animals and their uses in medical
10
research.
2. Techniques involved in proteomic studies.
10
3. Gut microbiome, prebiotics and probiotics.
10
4. a) Glucagon-like peptide -1 and its analogues.
5+5
b) Anti-GAD antibody.
5. Techniques for determination of primary and quaternary structure of
10
proteins.
6. Reverse transcriptase-polymerase chain reaction (RT-PCR) and antigen
10
testing in COVID-19 diagnosis.
7. Laboratory tests for thyroid function evaluation and role of anti-TPO
10
antibodies in diagnosis of thyroid disorders.
8. Techniques of HLA typing & matching and disease association with different
10
HLA types.
9. Impact factor of a journal and H-index of an author.
10
10. a) CRISPR system in genetic engineering.
5+5
b) Calculation of sample size in animal studies.
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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
This post was last modified on 31 July 2021