Download DNB 2020 December Pathology Paper I Question Paper

Time: 3 hours

Max. Marks: 100

Important Instructions:

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• You are provided with 5 answer sheet booklets. Each individual answer sheet booklet consists of 10 pages excluding the covering jackets.
• Answers to all the questions must be attempted within these 5 answer sheet booklets which must be later tagged together at the end of the exam.
• No additional supplementary answer sheet booklet will be provided.
• Attempt all questions in order.
• Each question carries 10 marks.

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• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.

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• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. Describe the pathophysiology of hypovolemic shock. Discuss the expected autopsy findings in a case of death from hypovolemic shock due to upper GI bleed.

   10

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2. a) Enumerate “Pattern recognition receptors" of immune system.

   b) Spectrum of autoantibodies in SLE.

   5+5

3. a) Cellular and immunological interactions in atherosclerotic plaque.

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   b) Chemical nature of amyloid.

   5+5

4. a) Regulators of angiogenesis.

   b) Laboratory information system.

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   5+5

5. a) Significance of non-coding DNA.

   b) Triple repeat disorders of coding regions.

   5+5

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6. a) Telomeropathies.

   b) Inflammasomes.

   5+5

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7. a) Role of growth factors in tissue repair.

   b) Pathogenesis of ascites.

   5+5

8. a) Xenobiotics.

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   b) Pyroptosis and its role in health and disease.

   5+5

9. a) Cellular Housekeeping.

   b) Cyclin Dependent Kinase Inhibitors (CDKIs).

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   5+5

10. Pathophysiology of Covid-19.

    10

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