PHARMACOLOGY
PAPER-IV
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PHARM/D/20/34/IV
Time: 3 hours
Max. Marks:100
Important Instructions:
- You are provided with 5 answer sheet booklets. Each individual answer sheet booklet consists of 10 pages excluding the covering jackets.
- Answers to all the questions must be attempted within these 5 answer sheet booklets which must be later tagged together at the end of the exam.
- No additional supplementary answer sheet booklet will be provided.
- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts wherever appropriate.
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Write short notes on:
- Define drug repositioning with suitable examples. Describe the advantages of drug repositioning and challenges involved. 5+5
- Describe in brief about need and objectives of materiovigilance programme of India. 10
- Critically evaluate current status of therapeutics used in COVID-19 care. 10
- Recent advances in pharmacotherapy of heart failure. 10
- Enumerate newer anticoagulants. Describe in brief the mechanism of action and therapeutic uses of oral anticoagulants. 3+7
- What is evidence based medicine? What are the levels of evidence? 3+7
- Define polypharmacy with suitable example(s). Write briefly on its advantages and disadvantages of it. 3+7
- Describe general principles of hospital antibiotic policy. 10
- a) Periodic safety update report (PSUR). 5+5
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b) No observable adverse effect level (NOAEL). - Describe in brief vaccine-development process. How does it differ from drug-development process? 5+5
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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
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