FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
BIOCHEMISTRY
PAPER-II
BCHEM/J/20/03/II
Max. Marks:100
Important Instructions:
Attempt al questions in order.
Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Explain how:
4+6
if not managed properly within first five years of life.
b) Kreb's bicycle effectively links the fates of amino groups
and carbon skeleton of the amino acids.
2. a) Leukotriene synthesis, function, pathogenetic role and its inhibitors.
b) Excretion of cholesterol from human body.
3. Explain how:
4+3+3
a) Cyanide exert its toxicity and its toxicity managed.
animals and new born babies.
c) Thermodynamically unfavourable biochemical reactions occur in
human body.
4. a) Role of leptin in obesity.
b) Biochemical markers of malnutrition.
5. a) How is heme synthesized?
6+4
b) Write biochemical basis of presentation of porphyria cases with acute
6. Explain why:
4+3+3
a) Vitamin B12 deficiency leads to megaloblastic anaemia.
b) Folic acid should not be given alone when its deficiency coexists with
c) Histidine load test is negative in vitamin B12 deficiency.
7. Define dietary fiber. Classify them. Write their functions and therapeutic
2+2+4+2
uses.
-1-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
FINAL EXAM
JUNE 2020
BIOCHEMISTRY
PAPER-II
8. Explain why:
a) AMP concentration is a more sensitive indicator of the cell's energetic
state than that of ATP.
b) Deficiency of pyruvate kinase leads to haemolytic anaemia.
c) Patient on haemodialysis is administered carnitine to prevent
9. Write biochemical basis of physiological serum cholesterol homeostasis,
3+4+3
hypercholesterolemia in hypothyroidism and diabetes and their
management.
2+8
hypothyroidism can be differentiated by thyroid function testing in
laboratory.
************
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
BIOCHEMISTRY
PAPER-II
--- Content provided by FirstRanker.com ---
Time: 3 hoursBCHEM/J/20/03/II
Max. Marks:100
Important Instructions:
Attempt al questions in order.
--- Content provided by FirstRanker.com ---
Each question carries 10 marks.Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
--- Content provided by FirstRanker.com ---
Start the answer to a question on a fresh page or leave adequate space between two answers.Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Explain how:
4+6
--- Content provided by FirstRanker.com ---
a) Phenylketonuria causes mental retardation and skin pigment disorderif not managed properly within first five years of life.
b) Kreb's bicycle effectively links the fates of amino groups
and carbon skeleton of the amino acids.
2. a) Leukotriene synthesis, function, pathogenetic role and its inhibitors.
--- Content provided by FirstRanker.com ---
7+3b) Excretion of cholesterol from human body.
3. Explain how:
4+3+3
a) Cyanide exert its toxicity and its toxicity managed.
--- Content provided by FirstRanker.com ---
b) Thermogenin helps to maintain body temperature in hibernatinganimals and new born babies.
c) Thermodynamically unfavourable biochemical reactions occur in
human body.
4. a) Role of leptin in obesity.
--- Content provided by FirstRanker.com ---
5+5b) Biochemical markers of malnutrition.
5. a) How is heme synthesized?
6+4
b) Write biochemical basis of presentation of porphyria cases with acute
--- Content provided by FirstRanker.com ---
abdomen and cutaneous lesion.6. Explain why:
4+3+3
a) Vitamin B12 deficiency leads to megaloblastic anaemia.
b) Folic acid should not be given alone when its deficiency coexists with
--- Content provided by FirstRanker.com ---
vitamin B12 deficiency.c) Histidine load test is negative in vitamin B12 deficiency.
7. Define dietary fiber. Classify them. Write their functions and therapeutic
2+2+4+2
uses.
--- Content provided by FirstRanker.com ---
P.T.O.-1-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
FINAL EXAM
--- Content provided by FirstRanker.com ---
NATIONAL BOARD OF EXAMINATIONSJUNE 2020
BIOCHEMISTRY
PAPER-II
8. Explain why:
--- Content provided by FirstRanker.com ---
3+4+3a) AMP concentration is a more sensitive indicator of the cell's energetic
state than that of ATP.
b) Deficiency of pyruvate kinase leads to haemolytic anaemia.
c) Patient on haemodialysis is administered carnitine to prevent
--- Content provided by FirstRanker.com ---
development of hypoglycaemia.9. Write biochemical basis of physiological serum cholesterol homeostasis,
3+4+3
hypercholesterolemia in hypothyroidism and diabetes and their
management.
--- Content provided by FirstRanker.com ---
10. Define sub-clinical hypothyroidism. How primary, secondary and tertiary2+8
hypothyroidism can be differentiated by thyroid function testing in
laboratory.
************
--- Content provided by FirstRanker.com ---
-2-POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.