FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
HEMATOLOGY
PAPER-II
HEMAT/J/20/48/II
Max. Marks:100
Important Instructions:
Attempt al questions in order.
Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. a) Multiple myeloma diagnosis and indications for therapy.
3+3+4
c) First line therapy for newly diagnosed multiple myeloma.
2. a) Daratuzumab.
4+4+2
b) Selinexor.
3. Chronic myelomonocytic leukemia (CMML):
3+3+4
a) Diagnosis.
b) Prognosis.
4. a) List common parasites that cause eosinophilia.
3+3+4
b) What are causes of increased basophils?
c) How can you identify myeloid versus lymphoid hyper-eosinophilia?
5+5
b) How wil you diagnose chronic lymphocytic leukemia? How wil you
prognosticate?
6. a) What is secondary leukemia and therapy related leukemia?
b) How wil you diagnose, risk stratify and treat secondary acute myeloid
leukemia?
7. a) What is fresh frozen plasma, what does it contain? How is it prepared?
5+5
and precautions needed when using this blood product?
P.T.O
-1-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
HEMATOLOGY
8. a) What is leuodepletion of packed red blood cel s? What methods are 4+3+3
available?
b) What are the indications of leukodepleted blood products?
c) What is irradiation of blood products? Why is it done? What is the
9. a) Rare blood groups are precious; How can you store rare red blood
5+5
groups for long term in the blood bank?
b) What is Bombay blood group? How is it identified?
3+4+3
b) How wil you manage a patient with al o-immunization who requires blood
transfusion support for thalassemia intermedia and has a big spleen?
c) What are the requirements in a donor before platelet apheresis
************
-2-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
HEMATOLOGY
PAPER-II
--- Content provided by FirstRanker.com ---
Time: 3 hoursHEMAT/J/20/48/II
Max. Marks:100
Important Instructions:
Attempt al questions in order.
--- Content provided by FirstRanker.com ---
Each question carries 10 marks.Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
--- Content provided by FirstRanker.com ---
Start the answer to a question on a fresh page or leave adequate space between two answers.Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. a) Multiple myeloma diagnosis and indications for therapy.
3+3+4
--- Content provided by FirstRanker.com ---
b) Risk stratification of multiple myelomac) First line therapy for newly diagnosed multiple myeloma.
2. a) Daratuzumab.
4+4+2
b) Selinexor.
--- Content provided by FirstRanker.com ---
c) Minimal residual disease in multiple myeloma.3. Chronic myelomonocytic leukemia (CMML):
3+3+4
a) Diagnosis.
b) Prognosis.
--- Content provided by FirstRanker.com ---
c) Management.4. a) List common parasites that cause eosinophilia.
3+3+4
b) What are causes of increased basophils?
c) How can you identify myeloid versus lymphoid hyper-eosinophilia?
--- Content provided by FirstRanker.com ---
5. a) What is monoclonal lymphocytosis of undetermined significance?5+5
b) How wil you diagnose chronic lymphocytic leukemia? How wil you
prognosticate?
6. a) What is secondary leukemia and therapy related leukemia?
--- Content provided by FirstRanker.com ---
5+5b) How wil you diagnose, risk stratify and treat secondary acute myeloid
leukemia?
7. a) What is fresh frozen plasma, what does it contain? How is it prepared?
5+5
--- Content provided by FirstRanker.com ---
b) What is convalescent plasma for COVID-19? What tests are requiredand precautions needed when using this blood product?
P.T.O
-1-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
--- Content provided by FirstRanker.com ---
EXAMINATION HALL.FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
HEMATOLOGY
--- Content provided by FirstRanker.com ---
PAPER-II8. a) What is leuodepletion of packed red blood cel s? What methods are 4+3+3
available?
b) What are the indications of leukodepleted blood products?
c) What is irradiation of blood products? Why is it done? What is the
--- Content provided by FirstRanker.com ---
problem with irradiated blood products?9. a) Rare blood groups are precious; How can you store rare red blood
5+5
groups for long term in the blood bank?
b) What is Bombay blood group? How is it identified?
--- Content provided by FirstRanker.com ---
10. a) TRALI.3+4+3
b) How wil you manage a patient with al o-immunization who requires blood
transfusion support for thalassemia intermedia and has a big spleen?
c) What are the requirements in a donor before platelet apheresis
--- Content provided by FirstRanker.com ---
donation?************
-2-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
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