Download DNB 2020 June Immunohematology And Blood Transfusion Paper I Question Paper

Download Diplomate of National Board (DNB) 2020 June Immunohematology And Blood Transfusion Paper I Question Paper

FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
IMMUNOHEMATOLOGY AND BLOOD TRANSFUSION
PAPER-I
Time: 3 hours
IMHT/J/20/15/I
Max. Marks:100
Important Instructions:
Attempt all questions in order.
Each question carries 10 marks.
Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Describe the various sub-types of lymphocytes and discuss the role of T
5+5
lymphocytes in Transfusion Medicine.
2. Define platelet storage lesions, its clinical significance and discuss various
2+4+4
preventive measures for platelets storage lesions.
3. Draw coagulation cascade and discuss cel ular model of coagulation.
5+5
4. Describe the synthesis of antigens of ABO Blood group system and
5+5
molecular basis of Bombay phenotype.
5. a) Major Histocompatibility Complex.
5+5
b) Role of HLA in transfusion medicine.
6. a) Describe the role of Hepcidin in iron metabolism.
5+5
b) Discuss its application in diagnosis of iron deficiency anemia.
7. a) Define apoptosis.
2+3+5
b) Briefly describe method of detection of apoptosis.
c) Discuss applied aspects of apoptosis in stored platelet components.
8. a) What is randomized control trial?
2+3+5
b) Types of RCTs.
c) Plan RCT on use of calcium supplementation for prevention of
hypocalcaemia in apheresis donors.
9. a) Principle of polymerase chain reaction.
5+5
b) Its application in transfusion medicine.
10. Types of hypersensitivity reactions and their implication in blood transfusion.
5+5
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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.

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