FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
MEDICAL ONCOLOGY
PAPER-I
MED.ONCO./J/20/17/I
Max. Marks:100
Important Instructions:
Attempt all questions in order.
Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. a) Goldie-Coldman hypothesis.
2+4+4
c) Chemo-radiation.
2. a) Clinical application of pharmacogenomics.
3+4+3
b) Potential applications of Artificial Intel igence in Oncology.
3. a) Clinical applications of massive paral el sequencing.
3+4+3
b) Testing for KRAS mutations in Oncology.
c) Epigenetics in cancer.
2+4+4
b) Microsatel ite instability.
c) Immunotherapy of colon cancer.
5. a) Tumour mutation burden.
b) PERCIST 1.0.
c) Imaging of Neuro-endocrine tumours.
6. a) Targeted agents as radio-sensitizers.
3+3+4
c) Enumerate various approaches of immunotherapy with examples.
7. a) Sunscreens in prevention of skin cancer.
3+4+3
b) Assessment of risk for hereditary breast cancer.
8. a) Ebstein-Barr virus and human cancer.
4+3+3
b) Hepatitis C and cancer.
c) Vaccines in prevention of cancers due to infections.
-1-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
FINAL EXAM
JUNE 2020
MEDICAL ONCOLOGY
PAPER-I
9. a) Targeted therapies that inhibit VEGF signaling.
b) Adverse effects of VEGF inhibitors.
c) Newer VEGF molecules available for therapy.
10. a) Imaging studies in diagnosis and staging of ovarian cancer.
4+3+3
c) Tomosynthesis.
************
-2-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
MEDICAL ONCOLOGY
PAPER-I
--- Content provided by FirstRanker.com ---
Time: 3 hoursMED.ONCO./J/20/17/I
Max. Marks:100
Important Instructions:
Attempt all questions in order.
--- Content provided by FirstRanker.com ---
Each question carries 10 marks.Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
--- Content provided by FirstRanker.com ---
Start the answer to a question on a fresh page or leave adequate space between two answers.Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. a) Goldie-Coldman hypothesis.
2+4+4
--- Content provided by FirstRanker.com ---
b) Dose density in chemotherapy.c) Chemo-radiation.
2. a) Clinical application of pharmacogenomics.
3+4+3
b) Potential applications of Artificial Intel igence in Oncology.
--- Content provided by FirstRanker.com ---
c) Phase 0 clinical trials.3. a) Clinical applications of massive paral el sequencing.
3+4+3
b) Testing for KRAS mutations in Oncology.
c) Epigenetics in cancer.
--- Content provided by FirstRanker.com ---
4. a) Enumerate polyposis syndromes with risk of colon cancer.2+4+4
b) Microsatel ite instability.
c) Immunotherapy of colon cancer.
5. a) Tumour mutation burden.
--- Content provided by FirstRanker.com ---
2+4+4b) PERCIST 1.0.
c) Imaging of Neuro-endocrine tumours.
6. a) Targeted agents as radio-sensitizers.
3+3+4
--- Content provided by FirstRanker.com ---
b) Antibody-drug conjugates.c) Enumerate various approaches of immunotherapy with examples.
7. a) Sunscreens in prevention of skin cancer.
3+4+3
b) Assessment of risk for hereditary breast cancer.
--- Content provided by FirstRanker.com ---
c) Hormonal prevention of breast cancer.8. a) Ebstein-Barr virus and human cancer.
4+3+3
b) Hepatitis C and cancer.
c) Vaccines in prevention of cancers due to infections.
--- Content provided by FirstRanker.com ---
P.T.O-1-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
FINAL EXAM
--- Content provided by FirstRanker.com ---
NATIONAL BOARD OF EXAMINATIONSJUNE 2020
MEDICAL ONCOLOGY
PAPER-I
9. a) Targeted therapies that inhibit VEGF signaling.
--- Content provided by FirstRanker.com ---
4+3+3b) Adverse effects of VEGF inhibitors.
c) Newer VEGF molecules available for therapy.
10. a) Imaging studies in diagnosis and staging of ovarian cancer.
4+3+3
--- Content provided by FirstRanker.com ---
b) Role of interim PET-CT scan in DLBCL treatment.c) Tomosynthesis.
************
-2-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
--- Content provided by FirstRanker.com ---
EXAMINATION HALL.