FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
NEPHROLOGY
PAPER-I
NEPH/J/20/20/I
Max. Marks:100
Important Instructions:
Attempt al questions in order.
Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer al the parts of a single question together.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Vasoactive peptides in kidneys:
3+5+2
b) Their role electrolyte exchange regulation.
c) Clinical utility of endothelin antagonists.
2. Clinical studies:
7+3
clinical trials.
b) Analysis of variance and statistical significance.
3. Plasma cel dyscrasias:
3+3+4
b) Diagnostic criteria of monoclonal gammopathy of renal
significance.
c) Light chain induced renal damage.
4. Hypokalemia:
a) Diagnostic approach to a patient with hypokalemia.
b) Enumerate renal abnormalities in prolonged hypokalemia.
c) Management of Bartter's syndrome.
5. Peritoneal dialysis:
a) Relevance of PET test in CAPD.
b) What is three pore model of peritoneal membrane?
c) Define ultrafiltration failure in PD and its types.
6. Anaemia in chronic kidney disease:
a) Kidney's response to hypoxia.
b) Role of hepcidin.
c) Role of HIF stabilizers.
7. Magnesium metabolism:
a) Enumerate factors affecting reabsorption of magnesium in the kidney.
b) Pathophysiology of hypomagnesemia induced hypokalemia.
c) Describe pharmacologic management of hypomagnesemia.
P.T.O
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
NEPHROLOGY
PAPER-I
8. Podocytopathy:
4+4+2
b) Mechanism of podocyte injury in focal and segmental
glomerulosclerosis.
c) Role of parietal epithelial cel activation in glomerulus.
9. a) Describe the T cel receptor and antigen presenting cel interaction.
b) Costimulatory blockade.
10. Acute kidney injury in special situations:
5+5
a) COVID-19 infection.
************
-2-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
NEPHROLOGY
PAPER-I
--- Content provided by FirstRanker.com ---
Time: 3 hoursNEPH/J/20/20/I
Max. Marks:100
Important Instructions:
Attempt al questions in order.
--- Content provided by FirstRanker.com ---
Each question carries 10 marks.Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer al the parts of a single question together.
--- Content provided by FirstRanker.com ---
Start the answer to a question on a fresh page or leave adequate space between two answers.Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Vasoactive peptides in kidneys:
3+5+2
--- Content provided by FirstRanker.com ---
a) Enumerate vasoactive peptides in acting in kidneys.b) Their role electrolyte exchange regulation.
c) Clinical utility of endothelin antagonists.
2. Clinical studies:
7+3
--- Content provided by FirstRanker.com ---
a) Compare and contrast observational studies with randomisedclinical trials.
b) Analysis of variance and statistical significance.
3. Plasma cel dyscrasias:
3+3+4
--- Content provided by FirstRanker.com ---
a) Classification.b) Diagnostic criteria of monoclonal gammopathy of renal
significance.
c) Light chain induced renal damage.
4. Hypokalemia:
--- Content provided by FirstRanker.com ---
5+3+2a) Diagnostic approach to a patient with hypokalemia.
b) Enumerate renal abnormalities in prolonged hypokalemia.
c) Management of Bartter's syndrome.
5. Peritoneal dialysis:
--- Content provided by FirstRanker.com ---
4+3+3a) Relevance of PET test in CAPD.
b) What is three pore model of peritoneal membrane?
c) Define ultrafiltration failure in PD and its types.
6. Anaemia in chronic kidney disease:
--- Content provided by FirstRanker.com ---
4+3+3a) Kidney's response to hypoxia.
b) Role of hepcidin.
c) Role of HIF stabilizers.
7. Magnesium metabolism:
--- Content provided by FirstRanker.com ---
4+3+3a) Enumerate factors affecting reabsorption of magnesium in the kidney.
b) Pathophysiology of hypomagnesemia induced hypokalemia.
c) Describe pharmacologic management of hypomagnesemia.
P.T.O
--- Content provided by FirstRanker.com ---
-1-POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
--- Content provided by FirstRanker.com ---
JUNE 2020NEPHROLOGY
PAPER-I
8. Podocytopathy:
4+4+2
--- Content provided by FirstRanker.com ---
a) Podocyte pathophysiology.b) Mechanism of podocyte injury in focal and segmental
glomerulosclerosis.
c) Role of parietal epithelial cel activation in glomerulus.
9. a) Describe the T cel receptor and antigen presenting cel interaction.
--- Content provided by FirstRanker.com ---
5+5b) Costimulatory blockade.
10. Acute kidney injury in special situations:
5+5
a) COVID-19 infection.
--- Content provided by FirstRanker.com ---
b) Therapy with immune checkpoint inhibitors.************
-2-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
--- Content provided by FirstRanker.com ---