Download DNB 2020 December ClInIcal Immunology And Rheumatology Paper I Question Paper

Download Diplomate of National Board (DNB) 2020 December ClInIcal Immunology And Rheumatology Paper I Question Paper

FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2020
CLINICAL IMMUNOLOGY AND RHEUMATOLOGY
PAPER-I

Time: 3 hours
RHM/D/20/43/I
Max. Marks:100
Important Instructions:
You are provided with 5 answer sheet booklets. Each individual answer sheet booklet consists
of 10 pages excluding the covering jackets.
Answers to all the questions must be attempted within these 5 answer sheet booklets which
must be later tagged together at the end of the exam.
No additional supplementary answer sheet booklet will be provided.
Attempt all questions in order.
Each question carries 10 marks.
Read the question carefully and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. Discuss development of synovial joint. What are the sources of nutrition
6+4
for articular cartilage?
2. Discuss the structure and function of skeletal muscle. Write short note on (3+2)+5
excitation-contraction coupling.
3. Discuss different types of antigen presenting cells. Discuss the dendritic
5+5
cell based therapy of arthritis.
4. Discuss different dendritic cell subsets and the role they play in Rheumatic
3+7
disease.
5. Discuss about pro-inflammatory and regulatory monocytes. Draw flow
5+5
diagram of autophagy pathway.
6. Mechanism of calcineurin inhibitors and their role in lupus.
4+6
7. Differences between diagnostic and classification criteria and its
7+3
implication. Write short note on over-diagnosis and over-treatment.
8. Write about proteinases and their role in RA and OA.
5+5
9. Discuss IL-6 physiology and its implication in Rheumatic disease. Discuss
6+4
anti IL-6 trials in systemic sclerosis.
10. What is meta-analysis and what are the steps in doing it? Write short note
7+3
on Forest plot.
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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.

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