Download DNB 2020 June Pharmacology Paper I Question Paper

Download Diplomate of National Board (DNB) 2020 June Pharmacology Paper I Question Paper

FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
PHARMACOLOGY
PAPER-I
Time: 3 hours
PHARMA/J/20/34/I
Max. Marks:100
Important Instructions:
Attempt al questions in order.
Each question carries 10 marks.
Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer al the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. What is the importance of ABC transporters in drug absorption & 6+4
elimination? Enumerate the drugs which are significantly affected by ABC
transporters.
2. What is Pharmacovigilance? Outline National & International initiatives 2+4+4
taken for Pharmacovigilance. Discuss methods of causality assessment and
their role in Pharmacovigilance.
3. a) Fetal therapeutics.
5+5
b) Teratogenicity.
4. Discuss the application of clinical pharmacokinetic principles in drug
10
development.
5. a) Performance enhancing drugs.
5+5
b) Biosimilars.
6. What is Pharmacogenetics? Describe its principles. Discuss its role in 3+3+4
clinical practice.
7. Discuss how the principles of chronopharmacology can improve drug
10
therapy.
8. a) Explain nanoparticle dosage forms and their clinical applications.
5+5
b) Drug clearance.
9. What is NLEM and its importance? What are the important factors taken into
5+5
consideration for inclusion of drugs in the NLEM?
10. a) Inverse agonist.
5+5
b) Importance of drug food interaction.
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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.

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