NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
PHARMACOLOGY
PAPER-II
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Time: 3 hoursPHARMA/J/20/34/II
Max. Marks:100
Important Instructions:
Attempt al questions in order.
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Each question carries 10 marks.Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer al the parts of a single question together.
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Start the answer to a question on a fresh page or leave adequate space between two answers.Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Enumerate the different classes of antidepressant drugs with examples. 4+6
Discuss the mechanism of action, uses and side effects of selective serotonin
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reuptake inhibitors.2. a) Neurosteroids as potential drug targets.
5+5
b) Pharmacotherapy of pulmonary arterial hypertension.
3. Enumerate the drugs used for heart failure. Discuss the role of angiotensin 5+5
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receptor neprilysin inhibitors (ARNI) in the treatment of heart failure.4. a) Discuss the emergency management of diabetic ketoacidosis.
5+5
b) Discuss briefly newer hypolipidemic agents.
5. a) Therapeutic applications of monoclonal antibodies with suitable 5+5
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examples.b) Write mechanism of action, indications, adverse effects and important
precautions while prescribing methotrexate.
6. Enumerate antimalarials drugs. Discuss the pharmacotherapy of chloroquine 4+6
resistant malaria.
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7. a) Clinical applications of low dose aspirin.5+5
b) Fibrinolytics.
8. a) Give the rationale and management of precipitation of acute attack of gout 5+5
with al opurinol.
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b) What are the side effects with morphine therapy? Which drugs help incoping with these side effects?
9. a) Antileishmanial agents.
5+5
b) Protease inhibitors.
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10. Discuss the role of hematopoietic growth factors in anti-cancer chemotherapy 5+5************
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
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