NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
PHARMACOLOGY
PAPER-II
--- Content provided by FirstRanker.com ---
Time: 3 hoursPHARMA/J/20/34/III
Max. Marks:100
Important Instructions:
Attempt al questions in order.
--- Content provided by FirstRanker.com ---
Each question carries 10 marks.Read the question careful y and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer al the parts of a single question together.
--- Content provided by FirstRanker.com ---
Start the answer to a question on a fresh page or leave adequate space between two answers.Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Outline the differences between Intent to Treat and Per Protocol analyses. 5+5
Explain the advantages and disadvantages of each of them.
--- Content provided by FirstRanker.com ---
2. Discuss experimental methods for evaluation of a potential analgesic10
agent.
3. a) Parametric Versus Non-Parametric tests.
5+5
--- Content provided by FirstRanker.com ---
b) Confidence Intervals.4. Discuss the constitution & functions of Institutional Animal Ethical
5+5
Committee (IAEC).
5. a) Sample size calculation in clinical trials.
--- Content provided by FirstRanker.com ---
5+5b) H index.
6. a) Describe High-throughput Drug Screening Methods
5+5
b) Discuss the importance and principle of high pressure liquid
--- Content provided by FirstRanker.com ---
chromatography.7. Discuss the experimental evaluation methods for a potential diuretic agent.
10
Add a note on LIPSCHITZ test.
8. a) Kaplan meir survival curve.
--- Content provided by FirstRanker.com ---
5+5b) Systematic Review.
9. a) R-Principles of Alternatives to Animal Experimentation.
5+5
b) Proteomics.
--- Content provided by FirstRanker.com ---
10. What is a forest plot? Where is it used? How wil you read and assess a2+3+5
study/studies with the help of it?
************
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
--- Content provided by FirstRanker.com ---
EXAMINATION HALL.