NATIONAL BOARD OF EXAMINATIONS
JUNE 2020
PHARMACOLOGY
PAPER-IV
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Time: 3 hours
PHARMA/J/20/34/IV
Max. Marks:100
Important Instructions:
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Attempt all questions in order.Each question carries 10 marks.
Read the question carefully and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
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Answer all the parts of a single question together.Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
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1. a) Role of placebo in therapeutics.
5+5
b) Role of surrogate markers in clinical trials.
2. Cardiovascular Outcome trials (CVOT).
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10
3. Status of various therapies in COVID-19.
10
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4. a) Microdosing Studies.5+5
b) Biosimilars.
5. a) Hemovigilance.
5+5
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b) Drug utilization metrics.6. What are the approaches to reduce antibiotic resistance in clinical use?
10
7. Salient features of the new drugs and clinical trials rule (2019) in India.
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10
8. a) Drug repurposing.
5+5
b) Microbiota in therapeutics.
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9. a) Good Clinical Practice.5+5
b) Waiver of Informed Consent in a Clinical Trial.
10. Status of malaria and dengue vaccines.
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10************
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
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