Download DNB 2020 December MedIcal Oncology Paper I Question Paper

Download Diplomate of National Board (DNB) 2020 December MedIcal Oncology Paper I Question Paper

FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2020
MEDICAL ONCOLOGY
PAPER-I
Time: 3 hours
MED.ONCO/D/20/17/I
Max. Marks:100
Important Instructions:
You are provided with 5 answer sheet booklets. Each individual answer sheet booklet consists
of 10 pages excluding the covering jackets.
Answers to all the questions must be attempted within these 5 answer sheet booklets which
must be later tagged together at the end of the exam.
No additional supplementary answer sheet booklet will be provided.
Attempt all questions in order.
Each question carries 10 marks.
Read the question carefully and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1.
a) Viruses and cancer.
3+4+3
b) Drug resistance mechanisms in cancer.

c) Chemotherapy related cancers.
2.
a) Hereditary colon rectal cancer.
3+4+3
b) Microsatellite instability.

c) KRAS and BRAF mutation in colon cancer.
3.
a) Antibody-drug conjugates.
3+4+3
b) Proteasome Inhibitors in cancer therapeutics.

c) mTOR inhibitors in treatment of cancer.
4.
a) Enumerate tyrosine kinase inhibitors.
3+4+3
b) Tyrosine kinase inhibitors in lung cancer.

c) Tyrosine kinase inhibitors in renal cell carcinoma.
5.
a) Principles of Radiotherapy.
3+4+3
b) Newer techniques of radiotherapy in CNS tumours.

c) Radiation sensitizer.
6.
a) Cell cycle.
3+4+3
b) List CDK inhibitors.

c) Indication of CDK inhibitors in breast cancer.
7.
a) Immune check point inhibitors.
3+4+3
b) Immune check point inhibitors toxicities.

c) Immune check point inhibitors in metastatic melanoma.
8.
a) NGS and its utility in cancer management.
3+4+3
b) Flow Cytometry in leukemia management.

c) Cytogenetics in cancer.
P.T.O.
-1-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.

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FINAL EXAM
NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2020
MEDICAL ONCOLOGY
PAPER-I
9.
a) Mutations in cancer pathogenesis.
3+4+3
b) Tumor mutation burden.

c) Role of MMR and MSI in cancer management.
10.
a) Image Guider Radiotherapy.
3+4+3
b) Cyber Knife.

c) Cobalt Radiotherapy.
*************
-2-
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.

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