Download DNB 2020 December Nephrology Paper I Question Paper

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FINAL EXAM

DECEMBER 2020

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NEPHROLOGY

PAPER-I

Time: 3 hours

Max. Marks: 100

NEPHRO/D/02/20/I

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Important Instructions:

• You are provided with 5 answer sheet booklets. Each individual answer sheet booklet consists of 10 pages excluding the covering jackets.
• Answers to all the questions must be attempted within these 5 answer sheet booklets which must be later tagged together at the end of the exam.
• No additional supplementary answer sheet booklet will be provided.
• Attempt all questions in order.

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• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.

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• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. a) Water handling by kidney.
   b) Etiology of hyponatremia.
   

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   c) Management of hypovolemic hyponatremia.

   4+3+3

2. a) Dialysis adequacy in hemodialysis.
   b) Different trials in hemodialysis adequacy.

   5+5

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3. a) Podocyte pathophysiology.
   b) Podocyte involvement in minimal change disease and FSGS.

   5+5

4. a) Role of antigen presenting cell in transplant immunology.
   b) Different types of cross-match and their relevance.

   5+5

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5. a) Glomerular ultrafiltration pressure.
   b) Factors affecting GFR.
   c) Conditions where single nephron GFR is increased.

   2+3+5

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6. a) Implications of FGF-23 in chronic kidney disease-mineral bone disease.
   b) Adynamic bone disease in chronic kidney disease and its management.

   5+5

7. a) Illustrate juxta-glomerular apparatus.
   b) Tubuloglomerular feedback.
   

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   c) Glomerulotubular balance.

   3+4+3

8. a) Structure of peritoneal membrane.
   b) Conditions associated with filtration failure.

   5+5

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9. a) Define chronic kidney disease of unknown origin (CKDu).
   b) Status of CKDu in India.
   c) Study for assessing CKDu in a village.

   2+4+4

10. a) Sodium glucose transporters in kidney.
    

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    b) Effects of SGL receptor inhibitor.

    5+5

P.T.O.

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