Dr. V. Murugan
MURUGAN - SPM THE SURE SHOT
Crohnbach's Alpha
? used to estimate reliability or internal
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consistency of a questionnaire? Values ranges- 0-1
MURUGAN - SPM THE SURE SHOT
Kappa statistics
? Used to measure the inter observer
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agreement(eg- X ray by two observers)? Values >0.75- excellent agreement
? Values 0.4-0.75- intermediate to good
agreement
? <0.4- poor agreement
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MURUGAN - SPM THE SURE SHOTLikelihood ratio (LR)
? measures diagnostic accuracy
? Positive LR sensitivity
1- specificity
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? Negative LR 1- sensitivityspecificity
MURUGAN - SPM THE SURE SHOT
Receiver operating characteristic
(ROC) curve
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? Graphical display of validity of test? Plotted between sensitivity and 1- specificity
? Maximum area under the curve is 1
MURUGAN - SPM THE SURE SHOT
Bland Altman analysis
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? Graphical method to compare twoquantitative measurement techniques
? Plotted between mean of two measures and
difference between two measures
?
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MURUGAN - SPM THE SURE SHOTSerial testing of screening test
? One test first if positive followed by second
test
? Decrease in sensitivity and increase in
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specificityMURUGAN - SPM THE SURE SHOT
Parallel testing of screening test
? Increase in sensitivity and decrease in
specificity
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MURUGAN - SPM THE SURE SHOTNested case control study
? It is a prospective study
MURUGAN - SPM THE SURE SHOT
Number needed to treat in RCT
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? It is number of patients needed to be treatedto prevent one bad outcome
MURUGAN - SPM THE SURE SHOT
Forrest plot in meta analysis
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MURUGAN - SPM THE SURE SHOTCorrelation coefficient (r)
? Strength and direction of relationship
between 2 variables
? r= -1 to +1
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MURUGAN - SPM THE SURE SHOTType 1 and type 2 error
MURUGAN - SPM THE SURE SHOT
Kolmorgov smirnov test
? Used to check the normal distribution of the
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testMURUGAN - SPM THE SURE SHOT
Likert scale (ordinal data)
MURUGAN - SPM THE SURE SHOT
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