Pharma D 3rd Year Pharmacology-II Important Questions

Pharma D 3rd Year (Third Year) Pharmacology-II  Important Question Bank

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Essay Questions Pharma D 3rd Year

1. Classify diuretics according to their sites of action. Explain the mechanism of action, pharmacological effects,
   therapeutic uses and adverse effects of loop diuretics.
2. Define signal transduction. Mention various kinase pathways.
   Explain any two kinase pathways.
3. Define antibiotics. Explain the general mechanism of action of various antibacterial agents.
   Discuss the pharmacology of penicillins.
4. Explain gene transcription and various factors that regulate transcription.
5. a) Classify anti-neoplastic agents with examples. b) Write the mechanism of action, therapeutic uses of methotrexate
6. Define Protein. Discuss the mechanism and various steps involved in Protein synthesis.
7. Discuss the recombinant DNA technology and its Pharmaceutical applications with
   examples
8. Discuss the life cycle of malarial parasite. Classify anti-malarial drugs and explain mechanism of action, adverse effects and
   therapeutic uses of chloroquine.
9. What are quinolones? Write the spectrum of activity, mechanism of action therapeutic uses and adverse
   reactions of ciprofloxacin.
10. Classify anti cancer drugs with suitable examples. Write the mechanism of actions, therapeutic uses and adverse effects of paclitaxel.
    Add a note on hormones as anticancer drugs.
11. What is recombinant technology?
    Explain the principle, gene transfer technologies and applications of the same.
12. Classify anticancer drugs. Explain the pharmacology of alkylating agents.
13. Classify the antiplatelet drug. Write the mechanism of action, adverse drug reaction and therapeutic uses of
    clopidogrel.
14. Write the mechanism of action, adverse drug reaction and therapeutic uses of
    clopidogrel.
15. What is recombinant technology?
    Explain the principle, gene transfer technology and applications of the same.
16. Classify anticoagulants with examples and explain the pharmacology of heparin.
17. Classify anti-microbial agents with suitable examples and mechanism action of
    tetracycline antibiotics.
18. Explain the pharmacology of furosemide.
19. Define diuretics. Classify the diuretic according to their site of action and brief the
    loop diuretics.
20. Classify the immunosuppressant. Write the mechanism of action, adverse drug
    reaction, and therapeutic uses of mycophenolate mofetil.
21. Define cancer. Classify the anticancer drugs with example, write the Mechanism
    and therapeutic uses of antimetabolite.
22. Explain gene transcription and various factors that regulate transcription.
23. Classify the Drugs used in treatment of Malaria with suitable example. Write the
    mechanism of action, pharmacokinetic, adverse effect and use of Chloroquine.
24. Classify Antiviral drugs, Pharmacological actions and therapeutic uses.
25. Write about various pathway involved in signal Transduction and Ion Channels
26. What is DNA replication? Write about Eukaryotic DNA replication.
27. With suitable example, explain Gene transfer in a Plasmid. Add a note on
    applications of recombinant DNA technology.
28. How cell cycle is regulated? Explain the different phases of cell cycle and factors
    regulating it.
29. Classify Aminoglycoside antibiotics. State the Pharmacological actions,
    mechanism of action and therapeutic uses.
30. What is the source and mode of transmission of TB? Explain the treatment
    procedure and precautions to be taken in TB treatment.
31. What are Thiazide Diuretics? Give example. Write the Pharmacological action,
    therapeutic uses and adverse reactions of any one Thiazide Diuretics
32. Explain the cell signal transduction pathways involving Kinases
33. Classify Macrolide antibiotics and Pharmacological actions with uses
34. Define Biosensors. Write details about types and applications of Biosensors.
35. Classify Anti-viral agents with suitable examples and mechanism of action,
    pharmacokinetics and adverse effect of zidovudine.
36. Define Gene therapy. Write about gene targeting and gene mapping
37. Define Antibiotics. Classify penicillin antibiotics, write the pharmacology of
    Amoxicilliin and Calvunic acid.
38. Classify Anti-cancer drugs with suitable example. Write the mechanism and
    therapeutic uses of alkylating agents
39. Explain the mechanism of action, spectrum of activity, therapeutic uses and
    adverse reaction of: a) Sulfamethoxazole b) Ciprofloxacin
40. Discuss recombinant DNA technology and its pharmaceutical applications with
    examples.
41. What is RNA processing and write about Gene sequencing?
42. Define protein. Discuss the mechanisms and various steps involved in protein
    synthesis with suitable examples
43. Classify diuretic agents with suitable examples. Write the pharmacological action,
    therapeutic uses and adverse reactions of furosemide
44. Define cell cycle. Explain chromatin structure and flow of genetic information.
45. Classify Anti-malarial agents with suitable examples and write the mechanism of
    action, pharmacokinetics and adverse effect of chloroquine.
46. Classify Anti-microbial agents based on the mechanism of action. Brief on the
    spectrum of activity along with the mechanism of action of sulfonamide
    Antibiotics.
47. Explain the Gene transcription and various factors that regulate gene transcription.
48. Explain protein synthesis, its mechanism and altered gene functions
49. Classify Anti-tubercular agents and write the mechanism of action therapeutic uses
    and adverse effects of isoniazid.
50. Classify Anti Cancer drugs. Explain about Alkylating agents.
51. Write the mechanism of action, spectrum of action, adverse effects and therapeutic
    use of Ciprofloxacin.
52. Discuss the recombinant DNA technology and its pharmaceutical applications
53. What is Cell Signaling? Explain any two kinase signal transduction pathway

Short Questions

1. Write a note on potassium sparing diuretics.
2. Write a note on anti amoebic drugs
3. State the mechanism of action and advantage of low molecular heparin.
4. Write a note on haematinics
5. Write the MOA of Dapsone and its therapeutic effects.
6. MAP kinase pathway
7. Chronic toxicity studies.
8. Biosensors
9. What are macromolecules and write on their functions?
10. Plasma expanders
11. Therapeutic uses of ciprofloxacin.
12. Anti-coagulants
13. Amphotericin B.
14. Chemotherapy involved in leprosy.
15. Monoclonal antibodies as Immuno-suppressants
16. Biosensors
17. Gene therapy targets.
18. Anti-platelet agents with a note on mechanism of action of aspirin
19. MAP kinase pathway
20. Mechanism of action and drug interaction involving warfari
21. Potassium sparing diuretics
22. Anti-amoebic drugs.
23. Acute toxicity studies
24. Fluroquinolines
25. Mechanism of action, adverse effect, resistance and uses of chlorampenicol
26. Cell cycle regulators and modifiers
27. Anti-platelet agents and write MOA of aspirin.
28. Drugs used in protozoal infections
29. Gene expression
30. What is Multi Drug Resistance? How it can be controlled?
31. Explain the factors contributing mutations
32. Write a note on subacute toxicity studies.
33. What is mean by transcription? How it is regulated?
34. Give the rationale for the following combination:
    a) Sulbactum with Imepenam b) INH, Rifampicin and Ethambutol
35. Write the therapeutic uses and adverse reactions
    a) Zidovudine b) Metronidazole
36. Classify anticancer drugs based on its mechanism of action with
    suitable examples.
37. Chemotherapy involved in Leprosy
38. Classify antifungal antibiotic, write the MOA of AZOLE derivatives.
39. Sulphonamides and Amino glycoside antibiotics
40. Sub-acute and Chronic Toxicity studies
41. Plasma expanders
42. Macromolecules and Large Macromolecular assemblies
43. Brief the Nucleotide Reverse Transcriptase inhibitors
44. Define antidiuretic. Write receptor and clinical uses of vasopressin
45. Write note on Anticoagulants.
46. Mutation
47. Classify the anti TB Drugs. Write the treatment of TB as per DOTS.
48. Explain various mechanism of development of bacterial resistance to antibiotics.
49. Write a note on anti amoebic drugs
50. Write a note on co-trimoxazole.
51. Explain the importance of preclinical toxicity studies
52. Write the therapeutic uses of ciprofloxacin
53. Gene therapy targets
54. Janus kinase pathway.
55. Potassium sparing diuretics.
56. Write a note on plasma volume expander.
57. Classify the protein synthesis inhibitors and give short note on tetracycline
58. Classify the immunosuppressants and its clinical application
59. Histone deacetylase
60. Recombinant technology and its application
61.  Gene therapy targets.
62. Types of mutation.
63. stones
64. Histones
65. Janus kinase pathway.
66. Subacute toxicity studies
67. m-TOR inhibitors.
68. Amphotericin
69. Antibiotic resistance
70. Mechanism and therapeutic uses of vasopressin.
71. Oral anticoagulants.
72. What are macromolecules? Give its functions.
73. Write a note on gene mapping
74. What are the vectors used in gene transfer?
75. What is DNA replication? Give its importance.
76. Write a note on acute toxicity studies.
77. What are anti diuretic hormones? Give its therapeutic uses.
78. Write a note on loop diuretics
79. Write a note on anti amoebic drugs.
80. Write a note on fibrinolytic agents.
81. What is Aldosterone antagonist? Give its mechanism of action and therapeutic uses.
82. What is chronic toxicity study? Explain its importance in preclinical studies
83. Write a note on Furosemide
84. Write a note on immunosuppressive corticosteroids.
85. What are Plasma Expanders? Give its therapeutic uses.
86. Write a note on Oncogenes
87. Write a note on treatment of TB as per WHO.
88. Write a note on Biosensors
89. Explain the mechanism of development of bacterial resistance to antibioti
90. State the mechanism of action and advantage of low molecular Heparin.
91. Write a note on haematinics
92. Write a note on Heparin antagonist
93. Write the therapeutic uses of ciprofloxacin
94. Give the therapeutic uses and mechanism of actions
    of metronidazole and pyrimethamine.
95. Give the mechanism of action and side effects of co-trimoxazole
96. Write a note on Mutation
97. Give the category, mechanism of action and side effects
    of Tacrolimus.
98. Gene therapy
99. Biosensors
100. MAP kinase pathway
101. Ion channels
102. Chronic toxicity studies
103. Calcineurin inhibitors
104. Classify anti leprotic drugs and discuss about dapsone.
105. Aminoglycoside antibiotics
106. Potassium-sparing diuretics
107. Mechanism of action and drug interactions involving warfarin.
108. Altered gene functions.
109. Histone deactyalses
110. Cell cycle regulators and modifiers.
111. Acute toxicity studies.
112. Monoclonal antibodies as immunosuppressants.
113. Nucleoside and nucleotide reverse transcriptase inhibitors
114. Amphotericin B.
115. Tetracycline
116. Receptors and therapeutic uses of vasopressin
117. Clopidogrel

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Above question papers are applicable for below universities

Pondicherry University
NTR University of Health Sciences, VijayWada
Gandhi Institute of Technology and Management (GITAM University) Deemed, Visakhapatnam
Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati
Srimanta Shankardeva University of Health Sciences
Statutory Autonomous, AIIMS
Aryabhatta Knowledge University, Patna
Indira Gandhi Instt of Medical Sciences (Deemed University), Patna
B.N. Mandal University
Veer Kunwar Singh University,Bihar
Ayush and Health Sciences University, Raipur
Punjab University
Chhattisgarh Ayush and Health Sciences University, Raipur
Guru Gobind Singh Indraprastha University
University of Jamia Hamdard (Hamdard University)
Delhi University
Goa University
Gujarat University
Saurashtra University
Hemchandracharya North Gujarat University,Patan
MS University of Baroda
Veer Narmad South Gujarat University
Maharaja Krishnakumarsinghji Bhavnagar University
KSKV Kachchh University, Bhuj
Parul University, Vadodara
Sardar Patel University
Sumandeep Vidyapeeth University (Deemed), Vadodra
PT. B.D. Sharma University of Health Sciences, Rohtak
Maharishi Marakandeshwar University (Deemed), Ambala
Himachal Pradesh University
Maharishi Marakandeshwar University, Kumarhatti, Solan
Jammu University
Kashmir University
Deemed University, Jammu & Kashmir
Kolhan University, Chaibasa
Vinoba Bhave University
Ranchi University
Rajiv Gandhi University of Health Sciences
KLE Academy of Higher Education & Research (Deemed), Belgaum
JSS University, Mysore
Manipal Academy of Higher Education (Deemed University), Manipal
Nitte University (Deemed), Mangalore
Sri Devaraj Urs Academy of Higher Education and Research (Deemed University), Kolar
Sri Siddhartha Academy of Higher Education, Tumkur
Yenepoya University of Health Sciences (Deemed), Mangalore
Kerala University of Health Sciences, Thrissur
Amrita Vishwa Vidyapeetham University (Deemed), Coimbatore
Calicut University
Mahatma Gandhi University, Kerala
Barkatullah University
Madhya Pradesh Medical Science University, Jabalpur
Dr. Harising Gour University,Sagar
Jiwaji University
Devi Ahilya Vishwa Vidyalaya
Rani Durgavati Vishwa Vidyalaya, Jabalpur
Peoples University, Bhopal
Vikram University, Ujjain
AP Singh University
Maharashtra University of Health Sciences, Nashik
Bharati Vidyapeeth University (Deemed), Pune
Dr. D Y Patil University (Deemed), Pimpri, Pune
D.Y. Patil Education Society (Deemed University), Kolhapur
Datta Meghe Instt. of Medical Sciences (Deemed University), Nagpur
Krishna Institute of Medical Sciences University (Deemed), Karad
MGM Institute of Health Sciences (Deemed University), Navi Mumbai
Padmashree Dr. D Y Patil University (Deemed), Navi Mumbai
Pravara Institute of Medical Sciences (Deemed University), Ahmednagar
Manipur University
North Eastern Hill University, Shillong
Utkal University
Sambalpur University
KIIT University (Deemed), Bhubaneswar
Berhampur University
North Odisha University, Baripada, Odisha
Vinayaka Missions University (Deemed), Salem
Statutory Autonomous, Puducherry
Sri Balaji Vidyapeeth (Deemed University), Pondicherry
Bharath University (Deemed), Chennai
Adesh University, Bathinda
Baba Farid University of Health Sciences,Faridkot
Rajasthan University of Health Sciences
Rajasthan University
Jaipur National University (Private Univ.)
NIMS University (Deemed), Jaipur
Pacific Medical University, Udaipur
Sikkim Manipal Univ. of Health,Medical & Tech. Scs
Dr. MGR Educational and Research Institute (Deemed University), Chennai
The Tamilnadu Dr. MGR Medical University,Chennai
Chettinad Academy of Research and Education (Deemed University), Chettinad
Meenakshi University (Deemed), Chennai
Annamalai University
Saveetha University (Deemed), Chennai
Sri Ramachandra University (Deemed), Chennai
SRM Institute of Science & Technology
Kaloji Narayana Rao University of Health Sciences, Warangal
Tripura University
Hemwati Nandan Bahuguna Uttarakhand Medical Education University
Kumaon University, Nainital
Swami Rama Himalayan University, Dehradun
H. N. B Garhwal University
Uttrakhand Technical University, Dehradun
Deen Dayal Upadhyay Gorakhpur University, Gorakhpur
Dr. Ram Manohar Lohia Avadh University, Faizabad
King Georges Medical University,Lucknow
Dr B R Ambedkar University,Agra, U.P.
Glocal University, Saharanpur
Ch. Charan Singh Universitiy, Meerut
C.S.J.M. University, Kanpur
Mahatma Gandhi Kashi Vidyapith, Varanasi
Banaras Hindu University
Integral University, Lucknow
Aligarh Muslim University
Bundelkhand University
M J P Rohilkhand University
Santosh University
Sharda University, Greater Noida
Swami Vivekanand Subharti University, Meerut
Teerthanker Mahaveer University, Moradabad
Dr. Shakuntala Misra National Rehabilitation University, Lucknow
Mahatma Jyotiba Phule Rohilkhand University
Shri Venkateshwara University, Gajraula
West Bengal University of Health Sciences, Kolkata