Download RGUHS (Rajiv Gandhi University of Health Sciences) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2nd Year (Second Year) 2023 Feb 1030 Microbiology Paper I Rs 4 Previous Question Paper
Rajiv Gandhi University of Health Sciences, Karnataka
MBBS Phase ? II (CBME) Degree Examination - 13-Feb-2023
Time: Three Hours
Max. Marks: 100 Marks
MICROBIOLOGY ? PAPER I (RS-4)
Q.P. CODE: 1030
(QP contains two pages)
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS
2 x 10 = 20 Marks
1.
Mr. A, 40 yrs old male presents with painful vesicular lesions on the trunk region. He
informs the dermatologist that he is getting this for the second time in the same year.
Haematological investigations revealed that he had leucopenia with lymphocytopenia.
Tzanck smear from the vesicles showed cells with ground glass appearance. Further tests
revealed that he was reactive to HIV
a) What is the clinical condition the patient presented with?
b) Draw a neat labelled diagram of HIV
c) Discuss the laboratory diagnosis of HIV infection
d) Add a note on the post-exposure prophylaxis against HIV after needle stick injury
as per NACO guidelines
2.
A 16 year old girl presented with fever, abdominal pain, loose stools with blood and
mucus. Microscopic examination of stool showed many pus cells and non-motile bacilli
a) Enumerate the causative agents of dysentery
b) Discuss the pathogenesis and laboratory diagnosis of Shigellosis
c) Compare and contrast Amoebic dysentery and Bacillary dysentery
SHORT ESSAYS
8 x 5 = 40 Marks
3. 1. Laboratory diagnosis of Malaria
4. 2. Define cytokines and discuss their role in immune response
5. 3. Give an outline of laboratory diagnosis of bacterial infections
6.
Laboratory diagnosis of enteric fever
7.
Discuss the mechanisms of drug resistance among bacteria with examples
8.
Write briefly on Sporotrichosis
9.
Delayed type hypersensitivity reaction
10. Etiopathogenesis and laboratory diagnosis of gas gangrene
SHORT ANSWERS
10 x 3 = 30 Marks
11. Mention the markers for acute hepatitis B infection
12. Define transport media and mention its uses
13. DEC provocation test
14. Travellers diarrhoea
15. Chronic muco-cutaneous candidiasis
16. Draw a neat labelled diagram of fertilized ovum of Ascaris lumbricoides
17. Laboratory diagnosis of Leprosy
18. Graft versus host reaction
19. Name the three agents causing Mycetoma
20. Laboratory diagnosis of cholera
Page 1 of 2
QP CODE : 1030
Rajiv Gandhi University of Health Sciences, Karnataka
Multiple Choice Questions
10 x 1 = 10 Marks
21 i) False statement about innate immunity is
A. Acts as first line of defence
B. Complement system plays role
C. Nonspecific
D. Imm
unological memory seen
21 ii
) The antibiotic that cannot be used for treatment of extended spectrum -lactamase
producing organisms
A. Ceftriaxone
B. Piperacillin ? tazobactam
C. Amikacin
D. Me
ropenem
21 ii
i) Active immunity is not acquired by
A. Vaccination
B. Immunoglobulin transfer
C. Infection
D. Va
ccination and immunoglobulins
21 iv)
Floatation technique is useful for the detection of
A. Larva of strongyloides
B. Fertilised eggs of Ascaris lumbricoides
C. Taenia eggs
D. Opercu
lated eggs of trematodes
21 v)
A cook in a hostel mess suffered from enteric fever 2 years back. The chronic carrier
state in this patient can be diagnosed by
A. Widal test
B. Blood culture
C. Vi Antibody test
D. Bo
ne marrow culture
22 i) Which of the following is the most recommended method for diagnosis of pediatric HIV
infection
A. DNA PCR
B. RNA PCR
C. Real time PCR
D. P24
antigen detection
22
ii) The most common agent causing traveller's diarrhoea is
A. Enteroaggregative E.coli
B. Norovirus
C. Rotavirus
D. Enterotox
igenic E.coli
22 iii) False statement about hyper infection syndrome
A. It is due to repeated autoinfection cycles
B. Caused by Strongyloides stercoralis
C. Seen in immunocompetent patients
D. Causes enteritis or Malabsorption
22 iv)
Koplik's spot in buccal mucosa is diagnostic of
A. Mumps
B. Measles
C. Erythema infectiosum
D. Rubell
a
22 v)
The granules discharged in mycetoma contain
A. Bone spicules
B. Fungal colonies
C. Pus cells
D. Digested tissue
******
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This post was last modified on 02 December 2024