Download RGUHS (Rajiv Gandhi University of Health Sciences) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2nd Year (Second Year) 2024 June 1028 Pharmacology Paper I Rs 4 Previous Question Paper
Rajiv Gandhi University of Health Sciences, Karnataka
MBBS Phase ? II (CBME) Degree Examination - 03-Jun-2024
Time: Three Hours
Max. Marks: 100 Marks
PHARMACOLOGY ? PAPER I (RS-4)
Q.P. CODE: 1028
(QP contains two pages)
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS
2 x 10 = 20 Marks
1.
Define Drug antagonism. Discuss the different types of drug antagonism with suitable
examples.
2.
A 75 year old patient presents with defective gait and posture, mask like face and
Sialorrhoea. On examination, he had rigidity, tremors and hypokinesia. He was diagnosed
to be suffering from Parkinsonism.
a) Classify Antiparkinsonian drugs with suitable examples
b) Discuss the Pharmacological actions and adverse effects of Levodopa
SHORT ESSAYS
8 x 5 = 40 Marks
3.
Therapeutic uses and adverse effects of Alpha Blockers
4.
Define Bioavailability of a drug. Explain four drug related factors affecting bioavailability
5.
Cardiovascular actions of Adrenaline
6.
Compare and contrast Physostigmine and Neostigmine
7.
Pharmacological actions and adverse effects of Aspirin
8.
Inhalational glucocorticoids in Bronchial asthma
9.
A 38 year old patient after surgery for fracture femur is given Metoclopramide for
antiemetic action.
a) Explain the rationale of using metoclopramide in this patient.
b) Write its adverse effects and uses.
10. A 30 year old patient is brought to hospital with delusional beliefs, auditory hallucinations,
restlessness, disturbed sleep and inappropriate behaviour. She was diagnosed to be
suffering from schizophrenia and prescribed Olanzapine.
a) Explain the rationale of using Olanzapine in this patient.
b) Write its advantages over conventional antipsychotics.
SHORT ANSWERS
10 x 3 = 30 Marks
11.
What is therapeutic drug monitoring (TDM)? Write two drugs requiring TDM
12.
Rationale of using Atropine in Organophosphorous compound poisoning
13.
Rationale of using Morphine in acute pulmonary oedema
14.
Write two adverse effects of Phenytoin. Why is phenytoin contraindicated in pregnancy?
15.
Write three nondepolarising skeletal muscle relaxants
16.
Name two anti-motility drugs. Why are they contraindicated in Shigella dysentery?
17.
Write Two advantages and Two disadvantages of selective Cox 2 inhibitors
18.
Name three antitussives
19.
Explain the concept of Essential medicines (drugs)
20.
Write three uses of Calcium Disodium edetate
Page 1 of 2
QP CODE : 1028
Rajiv Gandhi University of Health Sciences, Karnataka
Multiple Choice Questions
10 x 1 = 10 Marks
21 i) An 18 year old female patient is brought to hospital in an unconscious state following
accidental drug overdose. Which of the following route is desirable for administering the
antidote for this patient?
A. Oral
B. Transdermal
C. Intravenous
D. Subcutaneous
21 ii
) Which of the following is a prodrug?
A. Hydralazine
B. Levodopa
C. Paracetamol
D. Aspirin
21 ii
i) Apraclonidine is a congener of clonidine used for
A. Pain relief
B. Reducing Blood pressure
C. Reducing intraocular tension
D. Reducing
blood glucose
21 iv)
Atropine produces all the following actions EXCEPT
A. Tachycardia
B. Dryness of mouth
C. Mydriasis
D. Urinar
y incontinence
21 v)
A 8 year old boy was brought by the mother with momentary loss of consciousness. EEG
shows spike and wave pattern. Pediatrician made a diagnosis of absence seizures. Which
of the following drug is useful for absence seizures?
A. Phenobarbitone
B. Sodium Valproate
C. Phenytoin
D. Carbamazepine
22 i) Which of the following antipsychotic produces extrapyramidal side effects?
A. Chlorpromazine
B. Olanzapine
C. Quetiapine
D. Ar
ipiprazole
22
ii) Which antihistaminic drug produces less central nervous system depressant activity?
A. Diphenhydramine
B. Pheniramine
C. Promethazine
D. Cetriz
ine
22 iii) Which of the following drug cannot be administered by inhalational route in asthma
A. Montelukast
B. Ipratropium bromide
C. Budesonide
D. Sa
lbutamol
22 iv)
An anti-emetic can be used in a conscious patient suffering from poisoning due to all the
following EXCEPT
A. Iron
B. Diazepam
C. Kerosene
D. Par
acetamol
22 v)
Essential drugs are
A. Life saving drugs
B. Inert drugs
C. Drugs that meet the priority health care needs of the population
D. Drugs that have no therapeutic use
******
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This post was last modified on 02 December 2024