Download OU Pharm D Question Paper 1st Year 2018 1239 Medicinal Biochemistry

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FACULTY

Pharm D (6-YDC) I – Year (Main & Backlog) Examination, July 2018

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Subject: Medicinal Biochemistry

Time: 3 Hours Max.Marks: 70

Note: Answer all questions from Part – A. Any Five questions from Part – B.

PART – A (10x2 = 20 Marks)

1. Write the structural components of Eukaryotic ribosomes.

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2. What is free energy and free energy change?
3. Write a note on glycogen storage diseases.
4. Write the characteristics of vesicular transport systems across cell membranes.
5. What is anion gap?
6. Explain briefly different states of nitrogen balance.

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7. Explain the liver enzyme tests.
8. What is LDL-cholesterol and how it is measured from other components of lipid profile.
9. Write briefly the metabolic derangements in diabetes mellitus.
10. What is hemolytic jaundice? How is it diagnosed?

PART – B (5x10 = 50 Marks)

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11. Explain in detail prokaryotic translation process.
12. Write the mechanism involved in regulation of body's acid-base balance and maintenance of blood pH.
13. Explain the characteristics of reversible enzyme inhibition with their kinetics.
14. List out various renal function tests and explain the tests based on glomerular function of kidneys.
15. Explain HMP pathway and its significance.

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16. a) Write the procedure and interpretation of OGTT.
    b) Explain the role of hormones in carbohydrate metabolism.
17. a) Explain dye tests for excretory function of liver.
    b) Explain calcium and phosphate homeostasis in the body.
18. Explain ß – oxidation of saturated fatty acids and write the total energy yield from complete oxidation of one molecule of palmitic acid.

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