OU Pharm D Question Papers Last 10 Years 2010-2020 || Osmania University
Pharm. D (6 YDC) I-Year (Main & Backlog) Examination, July 2019
Subject: Medicinal Biochemistry
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Time: 3 Hours Max. Marks: 70
Note: Answer all questions from Part —A. Any five questions from Part-B
PART-A (10x2 = 20)
- Define Co-transport, Symport and antiport with examples
- Write a note on co-enzymes and cofactors
- Write a note on lipid storage disease
- Write the advantages of glucose tolerance test over other blood glucose estimation tests?
- Write the metabolic disorders of phenylalanine and tyrosine-metabolism
- What is creatinine clearance test? Write its significance
- What is nitrogen balance?
- Write a note on immunochemical tests used in diagnosis of viral diseases
- Write the diagnostic significance of SGOT and SGPT enzymes.
- Write a note on essential amino acids.
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PART B (5X10 = 50)
- Explain ß-oxidation of palmitic acid with its energetic.
- Explain HMP shunt and write its significance
- Explain Line weaver Burk plot. Discuss about reversible enzyme inhibition with examples
- Explain DNA replication and DNA repair mechanism
- What is biological oxidation? Explain the mechanism of ETC and its regulation
- Discuss the tests for hepatic dysfunction
- Explain in detail about RIA and discuss its applications in diagnosis
- Discuss in detail about gluconeogenesis and Write a brief account on glycogen storage diseases
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