Download OU Pharm D Question Paper 3rd Sem 2018 1254 Medicinal Chemistry

Download OU (Osmania University) Pharm D (Doctor of Pharmacy) 3rd Year (3rd Semester) 2018 1254 Medicinal Chemistry Previous Question Paper

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Code No. 1254
FACULTY OF PHARMACY
Pharm D (6?YDC) III ? Year (Main & Backlog) Examination, June 2018
Subject: Medicinal Chemistry
Time: 3 Hrs Max.Marks: 70
Note: Answer all questions from Part ? A. Any Five questions from Part ? B.
PART ? A (10x2 = 20 Marks)
1 Define scabicide with example.
2 Mention the type of hyperlipo proteinemia.
3 Give two examples with therapeutic use of polypeptide antibiotics.
4 Differentiate between disinfectant and antiseptic.
5 Write the chemical structure and uses of testosterone.
6 Define the term pro-drug and write application.
7 What is combinatorial synthesis?
8 Write the structure mode of action of fluconazd.
9 Write the mode of action of cardiac glycoside.
10 Classify antihelmintic agents.
PART ? B (50 Marks)
11 a) Write the classification of anti-malarial agents with one example from each class. 5
b) Write synthesis, mode of action: 5
i) Cefalexine
ii) Minocycline.
12 a) Write the S.A.R of cephalosporin and tline the synthesis of ampicillin. 5
b) What are antiarrhythmic drugs? Classify them with examples, write the structure
and uses of verapamil, phenytion, and propranolol 5
13 a) Write the S.A.R. of thiazide diurette. 5
b) What are calcium channel blocker? Describe their effect on cardiovascular
system. Write the synthesis of Warfarin. 5
14 Write the synthesis, mode of action of following drugs: 10
i) Propylthireacil
ii) Mebendazole
iii) Clofibrate
iv) Tolbutamide
15 a) Write the S.A.R of sulfonyl ureas. 5
b) Write the synthesis mode of action of:
i) Albendazole ii) Ketoconazole 5
16 a) Write the classification of antiviral drug with one example of each class. 5
b) Write the synthesis, mode of action of: 5
i) Ethanbutolal ii) Isoniazid
17 Write short notes on: 10
i) Anti-inflammatory steroid ii) Endocrine hormone
18 a) Classify antianginal agent with example. 5
b) Write the S.A.R of 7-chloro-4-amino quinolin. 5
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