Download OU B.Pharma 2-1 Year 2013 7209 Pharmaceutical Analysis I Question Paper

Download OU (Osmania University) B.Pharma 2-1 (2nd Year 1st Sem) (Bachelor of Pharmacy) 2013 7209 Pharmaceutical Analysis I Previous Question Paper

PHARMACY,LIBRARY,HYD
Code No. 7209
FACULTY OF PHARMACY
B. Pharmacy II  Year I  Semester (Main) Examination, November 2013
Subject : Pharmaceutical Analysis - I
(Chemical Analysis)
Time : 3 hours Max. Marks : 70
Note: Answer all questions. All questions carry equal marks.
1.a) i) Write a note on rejection of doubtful values. 6
ii) What are primary and secondary standard substances? Give examples. 8
OR
b) i) Define the terms :
A) Specificity B) Sensitivity 4
C) Linearity D) ruggedness
ii) Explain the calibration of volumetric flask. 4
iii) A substance was known to contain 15.20?0.03% of a component, A. The
results obtained by two experiments taking the same substance and employing
the same analytical method as follows : 6
Experiment  I : % of A : 15.0, 15.31, 15.16 and 15.10
Experiment  II : % of A : 15.30, 15.34, 15.36 and 15.36
Discuss the results with reference to accuracy and precision of the
measurements.
2.a) i) Calculate the pH of a 0.01 M acetic acid. (Dissociation constant pKa = 4.76). 4
ii) Write a note on different concepts of acid and bases. 6
iii) Write a note on common ion effect. 4
OR
b) i) Derive equations to calculate the pH value of aqueous solutions of salts
obtained from weak acid and strong base. 10
ii) Write a note on amphoteric substances by giving few examples. 4
3.a) i) Describe the various steps involved in gravimetric analysis. 10
ii) How do you prepare and standardize 0.1 N sodium thiosulphate? 4
OR
b) i) Explain in detail about redox indicators. 7
ii) Explain Volhards method for the determination of chlorides. 7
4.a) i) Write about different solvents and indicators used in non-aqueous titration. 7
ii) Discuss the theory and applications of complexometric analysis with examples. 7
OR
b) i) ExplainIodometry andIodimetry with examples. 7
ii) Write the principle and procedure involved in assay of calcium gluconate. 7
5.a) i) Calculate the number of moles of sodium hydroxide in 500 ml. of 0.1 M sodium
hydroxide solution. 4
ii) Calculate the percentage composition of the elements in Na
2
CO
3
[Na=23 ,
C = 12, O = 16]. 5
iii) 0.202 gm of a carbon compound on combustion gave 0.361 gm of CO
2
and
0.147 gm of water. Calculate the empirical formula of the compound. 5
OR
b) i) Write the mass balance equation for the following : 2x3=6
A) Reaction between ammonium hydroxide and sulphuric acid
B) Reaction between sodium carbonate and hydrochloric acid
ii) Calculate the percentage composition of the elements in Na
2
S
2
O
4
[Na = 23, S = 32, O = 16]. 5
iii) Calculate the molarity of 17 g of pure Na
2
CO
3
in 600 ml. of solution. 3
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