Download OU B.Pharma 3-1 Year 2017 1076 Medicinal Chemistry I Question Paper

Download OU (Osmania University) B.Pharma 3-1 (3rd Year 1st Sem) (Bachelor of Pharmacy) 2017 1076 Medicinal Chemistry I Previous Question Paper

.

Code No. 1076
FACULTY
B. Pharmacy 3/4 I ? Semester (Main) Examination, November 2017
Subject : Medicinal Chemistry ? I
Time : 3 hrs Max. Marks : 70
Note : Answer all questions. All questions carry equal marks.
1 a) What do y mean by prodru approach in dru desin? How is it achieved? 7
b) Write the importance of steric features of drus. 7
OR
c) Define and ive their sinificances for the followin : 4 x 3
i) Lipophilicity ii) Chelation iii) Partition coefficient
iv) Ionization
2 a) Explain the S.A.R. ofb adreneric blockin aents. 8
b) ive the synthesis and uses of i) Salbutamol ii) Mecamylamine HCl 3 x 2
OR
c) What are cholineric drus? Write the mode of action and S.A.R. 8
d) tline the synthesis and uses of the followin :
i) Dicyclomine ii) Meprobamate 2 x 3
3 a) Classify Ani hypertensives with examples and SAR of ACE inhibitors. 8
b) Write the synthesis and uses of clonidine and Dipyridamole. 3+3
OR
c) ive an accnt of : 7+7
i) Cardiotonic drus ii) Vasodilators
4 a) Add a note on positive inotropic aents. 8
b) Write the synthesis and uses of i) Amrinone ii) Tolbutamide 3+3
OR
c) Define and classify diabetes with examples. Write the MoA and uses of
carbonic antydrase inhibitors. 8
d) ive the synthesis and uses of followin :
i) Amiloride ii) Furosemide 6
5 a) Classify Anti histamine aents. ive the SAR of any two classes of H
1
?
Antihistaminics. 8
b) Write a note on proton pump inhibitors. 6
OR
c) Discuss in detail abt coaulants and anticoaulants. 6
d) Write the synthesis and MoA of followin : 4+4
i) Omeprazole ii) Diphenhydramine
******
FirstRanker.com - FirstRanker's Choice