Rajiv Gandhi University of Health Sciences, Karnataka
Post Graduate Degree Examination — JUNE 2016
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Time: Three Hours Max. Marks: 100 Marks
MD BIOCHEMISTRY
(Bio-organic chemistry, biophysical chemistry and biochemical techniques)
PAPER- I
(Revised Scheme)
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Q. P. CODE: 7315
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS 2 x 20 = 40 Marks
- Describe the blood buffers. Explain the interpretation of arterial blood gas analysis in various acid base disorders.
- Explain structure function relationship of proteins with suitable examples.
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SHORT ESSAYS 6 x 10 = 60 Marks
- Explain the principle and applications of immunoelectrophoresis.
- Explain the principle and applications of western blot technique.
- Ultra-centrifugation - principle and applications
- Ion selective electrodes
- High pressure liquid chromatography
- Applications of radioactive isotopes in diagnosis
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M.D. Degree Examination — JUNE 2016
[Time: 3 Hours] [Max. Marks: 100]
BIOCHEMISTRY
PAPER - II (Revised Scheme)
Q.P. CODE : 7316
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Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY 2 X 20 = 40 Marks
- Describe Eukaryotic protein biosynthesis. Add a note on the inhibitors.
- Discuss regulation of blood glucose level in detail
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SHORT ESSAY 6 X 10 = 60 Marks
- Metabolic fate of Glycine
- Significance of HMP shunt
- Important products from tyrosine
- Mutations - types and effects
- Metabolism of Adipose tissue
- B-oxidation of saturated 16 Carbon fatty acid
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Rajiv Gandhi University of Health Sciences
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M.D. Degree Examination — JULY 2016
[Time: 3 Hours] [Max. Marks: 100]
BIOCHEMISTRY
PAPER - III (Revised Scheme)
Q.P. CODE : 7317
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Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY 2 X 20 = 40 Marks
- Describe metabolism of calcium and various factors influencing its homeostasis. Add a note on calmodulin.
- Describe the structure, synthesis of hemoglobin.
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SHORT ESSAY 6 X 10 = 60 Marks
- Enzyme inhibitions: Mechanism and application of any two.
- Wilson’s disease.
- Balanced diet.
- Glycemic index.
- Biotrasformation.
- Name different types of collagen and enumerate any three disorders of collagen maturation.
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Rajiv Gandhi University of Health Sciences
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M.D. Degree Examination — JULY 2016
[Time: 3 Hours] [Max. Marks: 100]
BIOCHEMISTRY
PAPER - IV (Revised Scheme)
Q.P. CODE : 7318
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Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAYS 2 X 20 = 40 Marks
- Describe the various molecular changes leading to atherosclerosis. Explain the risk assessment and biochemical basis of the management of such patients.
- Classify and explain the different types of Proteinurias. Add a note on the newer methods of estimation of Glomerular function.
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SHORT ESSAYS 6 X 10 = 60 Marks
- Lactic acidosis.
- Human leucocyte antigens and association with diseases.
- Lysosomal storage diseases.
- Biochemical basis of hypertension.
- Diagnostic enzymes in hepato biliary diseases.
- Criteria of selection of assay procedure.
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