PTU B-Pharma 6th Semester May 2019 71037 PHARMACEUTICAL MICROBIOLOGY Question Paper

Roll No.

Total No. of Questions : 10

Total No. of Pages : 02

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B.Pharma (2011 to 2016) (Sem.-6)

PHARMACEUTICAL MICROBIOLOGY

Subject Code : BPHM-605

M.Code : 71037

Time: 3 Hrs.

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Max. Marks : 80

INSTRUCTION TO CANDIDATES :

1. SECTION-A is COMPULSORY consisting of FIFTEEN questions carrying TWO marks each.
2. SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.
3. SECTION-C contains FOUR questions carrying TEN marks each and students have to attempt any THREE questions.

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SECTION-A

Q1. Define the following :

1. Antiseptic
2. Disinfectants
3. Grams Staining

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4. Sterilization
5. Sterility testing

Differentiate between

6. Actinomycetes and Rickettsiae
7. Toxin and Toxoid

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8. Vitamins and antibiotics
9. Transcription and Translation
10. catguts and eye drops

Answer Briefly :

11. How following materials tested for sterility : 0.9% w/v, 500ml Sodium chloride injection and WFI

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12. What is the significance of D value?
13. What are culture media and how are they sterilized?
14. Why is it necessary to wrap brown paper before autoclaving?
15. What are the precautions to be taken while autoclaving empty test tubes or petriplates?

SECTION-B

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Q2. Give principle and procedure for staining techniques.

Q3. Give different methods for the evaluation of disinfectants and explain any two.

Q4. What is electron microscopy? Give its applications.

Q5. What is microbial assay? Give method for the assay of vitamins.

Q6. Write short note on :

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1. Diagnostic preparations
2. Structure of Bacterial cell

SECTION-C

Q7. Explain construction, working, principle and validation of horizontal Autoclave.

Q8. How Dephtheria toxoid vaccine and staphylococcus vaccine prepared?

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Q9. Explain method for the testing of sterility.

Q10 Write short note on :

1. Monitoring of sterilization process
2. BCG vaccine

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.

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