FACULTY OF ENGINEERING
5th Semester (CBCS) Examination
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Subject : Bio-Technology
Paper — II : Nucleic Acids & Bioinformatics
PART-A (5 X 4 = 20 Marks)
(Short Answer Type)
Note : Answer any FIVE of the following questions.
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- C-value paradox
- Enzymes of DNA replication
- Excision repair
- BLAST
- PDB
- Pairwise and multiple sequence alignment
- Pharmacogenomics
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PART - B (4 x 15 = 60 Marks)
(Essay Answer Type)
Note: Answer ALL from the questions.
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- (a) Compare structures of different forms of DNA with a neat labeled diagram.
OR
(b) Write a detailed note on different types of DNA sequences in eukaryotic genomes. - (a) What is DNA recombination? Explain homologous recombination.
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(b) Define mutation. Illustrate different types of mutations with examples. - (a) What is bioinformatics? Discuss the emergence of bioinformatics.
OR
(b) What is a biological database? How are they useful in biological research? - (a) What is genome annotation? Explain the role of bioinformatics in genome annotation.
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OR
(b) How does bioinformatics assist in drug discovery?
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