Download PTU M-Pharma 2019 May 1st Semester 74676 ADVANCED PHARMACOLOGY I Question Paper

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Roll No.

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Total No. of Questions : 06

Total No. of Pages : 02

M. Pharmacy (Pharmacology) (2017 & Onwards) (Sem.-1)

ADVANCED PHARMACOLOGY-I

Subject Code : MPL-102T

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M.Code: 74676

Time: 3 Hrs.

Max. Marks: 75

INSTRUCTIONS TO CANDIDATES :

1. Attempt any FIVE questions out of SIX questions.

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2. Each question carries FIFTEEN marks.

1. Write notes on following :

   1. Mechanism of action of general anesthetics. 5
   2. Biotransformation 5
   3. Antiplatelet drugs 5

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2. 1. Define neurotransmitters. What are the criteria for a chemical to be called a neurotransmitter? 6
   2. Discuss in detail glutamatergic transmission in CNS. What are the various glutamate receptors? 9

3. Answer why? Any five :

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   1. ACE inhibitors cause 3
   2. Antipsychotics cause extrapyramidal side effects 3
   3. Lag period with tricyclic antidepressants. 3
   4. Folic acid is called maturation factor 3
   5. Propranolol is used as antianxiety drug. 3

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   6. Rivastigmine is used in Alzheimer's disease. 3
4. 1. Describe the physiological actions of histamine. Enumerate and discuss the clinical uses of antihistamines. 9
   2. Briefly discuss about newer antiepileptics. 6

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5. 1. Discuss the pathophysiology of Parkinson's disease. Write a note on Levodopa. 10
   2. Define hypertension. What is the first line therapy for hypertension in pregnancy? Why? 5

6. Answer the following :

   1. G protein coupled receptors. 5

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   2. Concept of linear compartment model 6
   3. Statins 4

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.

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