Download PTU M-Pharma 2019 May 1st Semester 74678 CELLULAR and MOLECULAR PHARMACOLOGY Question Paper

Roll No.

Total No. of Questions : 06 Total No. of Pages : 02

M.Pharmacy (Pharmacology) (2017 & Onwards) (Sem.-1)

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CELLULAR & MOLECULAR PHARMACOLOGY

Subject Code : MPL-104T

M.Code : 74678

Time : 3 Hrs. Max. Marks: 75

INSTRUCTIONS TO CANDIDATES :

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1. Attempt any FIVE questions out of SIX questions.
2. Each question carries FIFTEEN marks.

1. Write notes on following (Any THREE) :

   1. Principles and applications of flow cytometry.
   2. Proteomics

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   3. Significance of polymorphism in drug therapy
   4. Pharmacogenomics
2. 1. Explain in detail mitogen activated protein kinase signalling and its role as drug target.
   2. Elaborate on biosimilars and their applications.

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3. Explain (Any THREE)

   1. Gene mapping and its applications
   2. GPCR's
   3. Necrosis

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   4. ELISA
4. 1. Define Gene Therapy. What are the various techniques of gene transfer?
   2. Discuss the principles and applications of polymerase chain reaction.

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5. Write notes on :

   1. Recombinant DNA technology and its applications.
   2. Micro array techniques.

6. Answer the following :

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   1. What are the basic equipments used in cell culture lab?
   2. Define Cell Lines. How cells are cultured in cell culture techniques?
   3. What is calcium influx assay? What are its application?

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.

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