Download SGBAU B-Pharma 2019 Summer 2nd Sem Sem II Pathophysiology New Question Paper

Time : Three Hours Max. Marks : 75

Notes: 1. Answer all questions.

2. Illustrate your answer necessary with the help of neat sketches.

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1. MCQ 20
   1. Low level of oxygen in blood is called as ----
      1. Anaemia
      2. Hypoxia
      3. Hypercapnia
      4. Cyanosis

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   2. Following are the risk factors for development of atherosclerosis.
      1. cigarette smoking
      2. High cholesterol
      3. both a & b
      4. None of these

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   3. A normal GFR in healthy adult individual is ------
      1. 120 ml/min
      2. 110 ml/min
      3. 80 ml/min
      4. 130 ml/min

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   4. Decrease in pH due to respiratory insufficiency is called as -----
      1. Respiratory alkalosis
      2. Respiratory acidosis
      3. Metabolic acidosis
      4. Metabolic alkalosis

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   5. Hyperkalemia indicates high serum level of -----
      1. Sodium
      2. Chloride
      3. Potassium
      4. Calcium

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   6. Gout occurs mainly due to -----
      1. Sod urate crystals
      2. Calcium oxalate crystals
      3. Sod. chloride crystals
      4. None of above

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   7. Parkinson's diseases occurs due to low concentration of ----- Neurotransmitter.
      1. Serotonin
      2. Acetyl Choline
      3. Dopamine
      4. GABA

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   8. Which of the following are different types of cellular adaptations.
      1. Atrophy
      2. Hypertrophy
      3. Metaplasia
      4. All of the above

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   9. Healing by primary intention is observed in ----
      1. abscess cavity
      2. Extensive burns
      3. Surgically sutured wound
      4. Macerated wound

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   10. Migration of cancerious cells from the site of origin to other part of body forming secondary tumors is called ----
       1. diapedesis
       2. Metastasis
       3. Proliferation
       4. None of above

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   11. Duodenal peptic ulcers are associated with.
       1. Achlorhydria
       2. Hypochlorhydria
       3. Normochlorhydria
       4. Hyperchlorhydria

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   12. What arc the symptoms of hepatitis.
       1. Fatigue
       2. Low fever
       3. Nausea
       4. All of the above

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   13. Which of the following is responsible for Wilson's disease.
       1. Iron
       2. Copper
       3. Lead
       4. Chromium

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   14. Environment risk factor for the development of asthma include
       1. Socioeconomic status
       2. Allergen exposure
       3. Exposure to tobacco smoke
       4. All of above

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   15. What are early signs & symptoms of rheumatoid artharitis.
       1. Joint pain, tenderness, redness & swelling.
       2. Loss of joint range of motion.
       3. Limping
       4. All of above

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   16. Which of the following substance secretion is responsible for chest pain in IHD.
       1. Lactic acid
       2. Acetic acid
       3. Formaldehyde
       4. Hydrochloric acid

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   17. The risk factor for type — 2 diabetes mellitus include.
       1. Family History
       2. Being overweight
       3. High intake of fat
       4. None of these

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   18. Primary, sites of infection of T.B. are all of the following except.
       1. Lung
       2. Tonsil
       3. Intestine
       4. Kidney's

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   19. Ketonuria is caused by all of the following except in.
       1. diabetes mellitus
       2. vomiting
       3. starvation
       4. Normal healthy person

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   20. HIV attacks a certain kind of cell in the immune system ----
       1. RBC's
       2. WBC's
       3. Platelets
       4. Epithelial cells

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2. Solve any two questions, 10x2
   1. What is ischemic hearth diseases? Explain etiology & clinical manifestation of IHD.
   2. Define Inflammation & explain mechanism of [nflammation in detail.
   3. Decfine etiology & pathogenesis of Cancer.

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3. Solve any seven questions 7x5
   1. Give a account on COPD.
   2. Discuss pathophysiology of theumatoid arthritis.
   3. Derfine and explain megaloblastic anaemia.
   4. Explain pathophysiology of peptic Ulcer.
   5. Wnte ashort note on AIDS.

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   6. Discuss urinary tract infection.
   7. Write a notc on Alzheimer's disease.
   8. Give pathophysiology of hypertension.
   9. Give detail account of Typhoid.

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