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 A Firstranker's choice .
 Pharmacology -1: BP'404 T
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P. Pages : 2 AW - 2351Max. Marks : 75
Time : Three Hours
Notes:
- Answer all questions.
- Illustrate your answer necessary with the help of neat sketches.
- Use of pen Blue/Black ink/refill only for writing the answer book.
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-  a) Multiple choice questions. 10 -  Receptor for Cholinergic system are - «a-receptors
- P -receptor
- o &p-receptors
- Muscarinic
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-  Following which are membrane transport mechanism- - Absorption
- Distribution
- Metabolism
- Active transport
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-  Which drug act as enzyme inverse. - Penicillin
- Benzodiazepines
- Streptomycin
- Sulphonamides
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-  Example of Antipsychotic drugs. - Chlorpromazine
- Pimozide
- Fluphenazine
- all the above
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-  Selective B1 -agonist is — - Propranolol
- Timolol
- Terbutaline
- Aspirin
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-  Serotonin is synthesized from — - L- Tryptopham
- L- Histidine
- Prostaglandins
- Interlukins
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-  D — Tubocurarine is an example of - Local anesthetics
- Sedatives
- Skeletal muscle relaxants
- General anesthetics
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-  Neurotransmitter GABA is - Excitatory
- Inhibitory
- Neutral
- None of these
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-  Alzheimer's is ------ disease. - Infective
- Neurodegenerative
- Respiratory
- Urinary
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-  Drug produces P'cological etfects through - Receptor
- Enzyme
- Hormones
- All of these
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-  Receptor for Cholinergic system are 
AW - 2351 1 PTO
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-  b) Objective type questions. - Enlist various phase — I — metabolic reaction.
- Enlist various mechanism by which drug act.
- Enlist factors modifying drug action.
- Define drug Interaction. Mention its types.
- Classify sedatives & Hyphotics.
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-  Long answer any two. 20 - Classify Adrenergic drugs. Discuss the pharmacology of Adrenaline in detail.
- Explain various routes of drug Administration.
- Classify Anti-epileptic Drugs. Discuss pharmacology of Phenytoin.
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-  Short answer any seven. ‘ 7+5 - Write in short about Phase-II bio-transtormation reaction.
- Classify Anti Parkinson's drugs. Write Mechanism of action of Carbidopa.
- Write various phases of clinical trials.
- Define Drug Interaction & explain Drug-tood & Drug-drug interaction € examples.
- Define Adverse drug reaction & explain it in short.
- Classify CNS stimulant. Write Pharmacology of Amphetamine.
- Write Pharmacological actions of Alcohol.
- Classify Anti-epileptic drug. Write MoA of Valproic acid.
- Write MoA, uses of Adverse effect of propranolol.
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AW -2351 2
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