Download SGBAU B-Pharma 2019 Summer 5th Sem Sem V Medicinal Chemistry I Question Paper

Download SGBAU (Sant Gadge Baba Amravati university) B.Pharma 2019 Summer (Bachelor of Pharmacy) 5th Sem Sem V Medicinal Chemistry I Previous Question Paper

P. Pages : 1
Time : Thrcc Hours
B. Pharm. F i?h Semester
35162 : Medicinal Chemistry - l : T-5.2
AW - 2308
t :1 I |
lul?lwshllsm?ildlll Max. Marks : 00
Notes :
1 All question carry equal marks.
2 Answer any ?ve questions.
3. Discuss the reaction. mechanism wherever necessary.
4 Use of pen BIuc/Black ink/re?ll only for Writing the answer book.
De?ne Drug metabolism. Explain in detail Glucuronic acid and sulfate conjugation
reactions.
What are prodrugs? Explain types of prodrugs with examples. Discuss various applications
of prodrugs.
De?ne and classify sympathomimetic agents with examples.
Explain biosynthesis ot?adrcncrgic neurotransmitters.
De?ne and classify amicholincrgic agents with examples.
Discuss SAR of anticholincrgic agents.
What are cholinergic agents? Explain SAR 0f Acetylcholine. Write a note on Reversible
cholinesterase inhibitors.
Enlist various physicochemical parameters which affect biolugical action of drugs. Explain
any four of them.
Write a note on any two.
a) B-adrenergic receptor antagonists.
b) Role of cytochrome P-450 monooxygenase in oxidativc metabolism of drugs.
c) Acetylation and mcthylation phase ? II reactions.
(1) Factors affecting Drug metabolism.
*************
AW - 2308 l
12
12
12
12
12
12
12