Download SGBAU BSc 2019 Summer 3rd Sem Biochemistry Intermediary Metabolism Question Paper

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B.Sc. Part-II (Semester-II1) Examination

BIOCHEMISTRY
(Intermediary Metabolism)

Time : Three Hours] [Maximum Marks : 80

Note :— (1) ALL questions are compulsory and carry equal marks.

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1. (A) Fill in the blanks :
   1. _________ is a first complex of ETC. ½
   2. Carbohydrate is stored in form of ______ in liver. ½
   3. _______ cycle is also termed as common metabolic pool. ½
   4. _________ is one of bile pigments. ½

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   (B) Choose the correct alternative :
   1. Lock and Key theory was proposed by :
      1. Leuwenhoek
      2. Koshland
      3. Darvin
      4. Emil Fischer

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   2. End product of aerobic glycolysis : ½
      1. Acetyl CoA
      2. Lactate
      3. Pyruvate
      4. CO2 and H2O

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   3. Glucose-6 phosphate is an allosteric inhibitor of : ½
      1. Glucokinase
      2. Hexokinase
      3. Phosphohexoisomerase
      4. None of the above

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   4. The following is required as reductant in fatty acid synthesis : ½
      1. NADH
      2. NADPH
      3. FMN
      4. FAD

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   (C) Answer in ONE sentence :
   1. Inhibitor 1
   2. Glycolysis 1
   3. Coenzyme 1
   4. Km 1

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2. Answer the following :
   1. Oxidative phase of HMP shunt 4
   2. Mechanism of oxidative phosphorylation 4
   3. Investment phase of glycolysis. 4
   OR
   1. Glyoxalate bypass 4
   2. Glycogen synthesis in Liver 4

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   3. CO2 generating steps of Kreb’s cycle. 4
3. 1. Describe biosynthesis of saturated fatty acids. 4
   2. Explain ß-oxidation of fatty acids. 4
   3. Explain in brief hydrolysis of triacylglycerols. 4

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   OR
   1. Describe in brief metabolism of ketone bodies. 4
   2. Discuss in brief biosynthesis of unsaturated fatty acids. 4
   3. Describe transport of fatty acids into mitochondrial matrix. 4
4. Describe in detail regulation of cholesterol metabolism. 12 OR Describe in detail biosynthesis of cephalin and lecithin. 12

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5. 1. Describe urea cycle in brief. 4
   2. Describe biosynthesis of cysteine. 4
   3. Describe biosynthesis of serine. 4
   OR
   1. Describe transamination and decarboxylation of amino acids. 4
   2. Describe biosynthesis of Tyrosine. 4

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   3. Explain catabolism of Methionine. 4
6. 1. Discuss the sources of atoms in purines. 4
   2. Describe in brief biosynthesis of adenine. 4
   3. Describe in brief regulation of purine biosynthesis. 4

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   OR
   1. Describe sources of atoms in pyrimidines. 4
   2. Explain in brief regulation of pyrimidine biosynthesis. 4
   3. Describe in brief biosynthesis of guanine. 4
7. Explain in detail degradation of heme pigment. 12 OR Describe in detail production of Bilirubin bile pigment. 12

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