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Code No: B4103
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R10 SET - 1
IV B. Pharmacy I Semester Advanced Supplementary Examinations, February - 2020
MEDICINAL CHEMISTRY-II
Time: 3 hours Max. Marks: 75
Answer any FIVE Questions
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All Questions carry Equal Marks
- a) Classify penicillins with examples. Discuss the SAR of Penicillins. (10M)
b) Write structure, nomenclature and synthesis of Amoxicillin. (5M) - a) With a neat scheme explain the hydrolytic reactions of Cephalosporins. (8M)
b) Write short notes on penams. (7M) - a) Discuss the amphoteric and chelation properties of Tetracycline. (8M)
b) Explain the SAR and toxicity of Tetracycline. (7M) - Discuss the following. (15M)
(a) Dihydrostreptomycin (b) Rifampicin - Write in detail on source, chemistry and physiological role of Vitamin D. (15M)
- a) Compare the structure and functions of Vitamin Ks. (6M)
b) Write in detail on chemistry and biological roles of vitamin E. (9M) - Discuss the chemistry and biological roles of (15M)
(a) Folic acid (b) Ascorbic acid - a) Write in detail brief on alphaglucosidase inhibitors. (7M)
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b) Write short notes on antithyroid drugs. (8M)
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