Download PTU M.Tech. Bio Tech 2nd Semester 23002 APPLIED IMMUNOLOGY Question Paper

Download PTU. I.K. Gujral Punjab Technical University (IKGPTU) M.Tech. Bio Tech 2nd Semester 23002 APPLIED IMMUNOLOGY Question Paper.

1 | M-23002 (S9)-292

Roll No. Total No. of Pages : 02
Total No. of Questions : 08
M.Tech.(Bio Tech.) (Sem.?2)
APPLIED IMMUNOLOGY
Subject Code : MTBT-102
M.Code : 23002
Time : 3 Hrs. Max. Marks : 100

INSTRUCTION TO CANDIDATES :
1. Attempt any FIVE questions out of EIGHT questions.
2. Each question carries TWENTY marks.

Q.1 a) Summarize the adaptive immune reactions that takes place in controlling bacterial
infections.
b) Write about the immunological privileged sites.
c) Discuss the graft versus host reactions.
Q.2 a) Describe the important steps of western blotting. Write the application of western
blotting.
b) Discuss the biosensor assay which is used to assess the interaction of ligand and
receptor?
Q.3 a) Explain the hypersensitive reaction which is associated with serum sickness.
b) Discuss any two cancer immunotherapy approaches.
Q.4 a) There is recent trend in peptides based vaccines. How these vaccine are prepared?
Write the role of HLA in consideration of peptide vaccine.
b) With examples, explain the role of adjuvants.
c) How conjugate vaccines are prepared?
Q.5 a) Discuss the different basis of graft rejection.
b) Describe the different phenomenon by which tumor gets evaded from immune
system?
FirstRanker.com - FirstRanker's Choice
1 | M-23002 (S9)-292

Roll No. Total No. of Pages : 02
Total No. of Questions : 08
M.Tech.(Bio Tech.) (Sem.?2)
APPLIED IMMUNOLOGY
Subject Code : MTBT-102
M.Code : 23002
Time : 3 Hrs. Max. Marks : 100

INSTRUCTION TO CANDIDATES :
1. Attempt any FIVE questions out of EIGHT questions.
2. Each question carries TWENTY marks.

Q.1 a) Summarize the adaptive immune reactions that takes place in controlling bacterial
infections.
b) Write about the immunological privileged sites.
c) Discuss the graft versus host reactions.
Q.2 a) Describe the important steps of western blotting. Write the application of western
blotting.
b) Discuss the biosensor assay which is used to assess the interaction of ligand and
receptor?
Q.3 a) Explain the hypersensitive reaction which is associated with serum sickness.
b) Discuss any two cancer immunotherapy approaches.
Q.4 a) There is recent trend in peptides based vaccines. How these vaccine are prepared?
Write the role of HLA in consideration of peptide vaccine.
b) With examples, explain the role of adjuvants.
c) How conjugate vaccines are prepared?
Q.5 a) Discuss the different basis of graft rejection.
b) Describe the different phenomenon by which tumor gets evaded from immune
system?
2 | M-23002 (S9)-292

Q.6 a) Write the role of different interleukins.
b) Mention the role of different molecular chaperons in class I MHC stabilization.
c) How super-antigen works? Also give examples.
d) Write on hapten carrier system.
Q.7 a) Describe the different steps involved in ELISA. Also explain competitive ELISA.
b) Differentiate between active and passive immunization.
c) How chimeric antibody is generated?
Q.8 a) How T helper is associated with B cell activation? Also write about ADCC.
b) Write about the affinity maturation.
c) Discuss the Tonegawa and Nozumi?s contribution in antibody diversity.








NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.

FirstRanker.com - FirstRanker's Choice