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Code No.8211
Paper : VI - A (DSE E-1
Time: 3 Hours
Part — A (5x3=15 Marks)
Answer any FIVE of the following eight questions:
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- Topoisomerases.
- Griffith's experiment.
- Inhibitors of RNA synthesis.
- Sigma factors.
- Genetic code.
- Ribosome structure.
- DNA polymerases I, II, III of E.coli.
- Structure of t-RNA.
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Part — B (3x15=45 Marks)
Answer all the following THREE questions:
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- (a) Write about models of replication and explain proof for semi-conservative model.
OR
(b) Describe the bi-directional replication model of E.Coli with a neat suitable diagram. - (a) Explain the initiation, elongation and termination of transcription in prokaryotes.
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(b) Explain the post-transcriptional modifications of eukaryotic m-RNA. - (a) What is Lac-operon? Explain the induction and repression of prokaryotic gene expression with reference to Lac operon.
OR
(b) Write about Translational events in prokaryotes.
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