This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
TKN/KS/16-6994
Fifth Semester Examination for the Degree of Bachelor of Pharmacy
PHARMACEUTICAL MEDICINAL CHEMISTRY – I
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5T2
[Max. Marks: 80
Time: Three Hours ]
N. B. : (1) Question No. 1 is compulsory.
(2) Solve any four questions from the remaining.
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(3) Draw neat labelled diagram wherever necessary.
- Solve any five of the following :-
- Draw structure, IUPAC Name, uses and synthesis of Phenytoin.
- Justify, why Carbidopa is given in combination with Levodopa.
- Discuss role of phosphodiesterase inhibitors.
- Justify 5, 5 disubstituted barbiturates shows sedative and hypnotic activity.
- How solubility affects absorption and distribution of drugs ?
- Draw structure, IUPAC name, uses and synthesis of Aspirin.
- What are Autocoids ? Explain in brief.
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5 x 4 = 20
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2. Describe phase I and Phase II reactions with examples. 15
Contd.
- (A) Define and classify Sedative and Hypnotics. Write mode of action and synthesis of one drug from Benzodiazepine class. 10
(B) Write note on antiepileptic agents. 5 - What are Narcotic analgesics and classify them? Explain SAR of any one class of opioid Analgesics. Write synthesis of any one drug. 15
- Classify Local anesthetics ? Discuss SAR, metabolism and synthesis of Lidocaine. 15
- (A) Define and classify Antipsychotics. 7
(B) Write structure, IUPAC names synthesis and uses of any two H – 1 antagonists. 8 - Write notes on (any three) of the following :-
- Receptor site theory
- Hypoglycaemic agents
- Alzheimer's disease
- Thyroid and anti – thyroid Hormones
- Bronchodilators.
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TKN/KS/16-6994 2
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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
--- Content provided by FirstRanker.com ---