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Download RTMNU B.Pharma 5th Semester 2016 Summer Pharmaceutical Medicinal Chemistry 1 Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 5th Semester 2016 Summer Pharmaceutical Medicinal Chemistry 1 Question Paper

This post was last modified on 19 January 2020

This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University


TKN/KS/16-6994

Fifth Semester Examination for the Degree of Bachelor of Pharmacy

PHARMACEUTICAL MEDICINAL CHEMISTRY – I

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5T2

[Max. Marks: 80

Time: Three Hours ]

N. B. : (1) Question No. 1 is compulsory.

(2) Solve any four questions from the remaining.

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(3) Draw neat labelled diagram wherever necessary.

  1. Solve any five of the following :-
    1. Draw structure, IUPAC Name, uses and synthesis of Phenytoin.
    2. Justify, why Carbidopa is given in combination with Levodopa.
    3. Discuss role of phosphodiesterase inhibitors.
    4. Justify 5, 5 disubstituted barbiturates shows sedative and hypnotic activity.
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    6. How solubility affects absorption and distribution of drugs ?
    7. Draw structure, IUPAC name, uses and synthesis of Aspirin.
    8. What are Autocoids ? Explain in brief.

5 x 4 = 20

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2. Describe phase I and Phase II reactions with examples. 15

Contd.

  1. (A) Define and classify Sedative and Hypnotics. Write mode of action and synthesis of one drug from Benzodiazepine class. 10
    (B) Write note on antiepileptic agents. 5
  2. What are Narcotic analgesics and classify them? Explain SAR of any one class of opioid Analgesics. Write synthesis of any one drug. 15
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  4. Classify Local anesthetics ? Discuss SAR, metabolism and synthesis of Lidocaine. 15
  5. (A) Define and classify Antipsychotics. 7
    (B) Write structure, IUPAC names synthesis and uses of any two H – 1 antagonists. 8
  6. Write notes on (any three) of the following :-
    1. Receptor site theory
    2. Hypoglycaemic agents
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    4. Alzheimer's disease
    5. Thyroid and anti – thyroid Hormones
    6. Bronchodilators.
    5x3=15

TKN/KS/16-6994 2

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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University

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