Download RTMNU B.Pharma 5th Semester 2016 Summer Pharmaceutics V (Physical Pharmacy) Question Paper

TKN/KS/16-6993

Fifth Semester Examination For the Degree of Bachelor of Pharmacy

PHARMACEUTICS V (PHYSICAL PHARMACY)

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5T1

Time: Three Hours ] [Max. Marks: 80

N. B. : (1) Question No.1 is Compulsory.

(2) Attempt any Four questions from the remaining.

(3) Draw neat labeled diagram wherever necessary.

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(4) Discuss the reaction, mechanism wherever necessary.

(5) Use of electronic calculator is permitted.

(6) Assume suitable data wherever necessary.

1. Solve any Five :-
   1. Emulsions are generally milky. Justify.
   2. Define HLB. Classify surfactants according to HLB scale.

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   3. What are lyophobic colloids ?
   4. Differentiate flocculated and deflocculated suspensions.
   5. How are micro emulsions different from emulsion.
   6. Define spreading coefficient. Write significance of -ve spreading coefficient.
   7. Explain in short mechanism of particle consolidation.

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   5x4=20

Contd.

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2

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2. Explain in detail factors affecting micelle formation.
3. How is charge developed on a particle dispersed in a medium ? Define zeta potential and explain its role in stability of dispersed system.
4. 15
5. Explain the methods to determine molecular weight of colloids.
6. 15

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7. 1. Explain adsorption of gases on solid surface.
   2. 7
   3. Describe adsorption technique for surface area determination.
   4. 8

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8. What are fundamental and derived properties ? Explain particle size determination by sedimentation method.
9. 15
10. Write short notes on any two :—
    1. Stabilization of emulsion.
    2. Peptization and coacervation of colloids.
    3. Donnan Membrane equilibrium.

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    4. Controlled flocculation.
11. 15

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430