Download RTMNU B.Pharma 5th Semester 2017 Summer Pharmacology 3 Question Paper

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B.Pharm. Semester—V (C.B.S.) Examination

PHARMACOLOGY-III

Paper-3

Time: Three Hours] [Maximum Marks : 80

Note :- (1) Question No. 1 is compulsory.

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(2) Attempt any four questions out of remaining.

(3) Draw neat labelled diagrams wherever necessary.

1. Justify use and mechanism of action of following (any five): 5×4=20
   1. Chlorpromazine
   2. Sodium valproate
   3. Morphine

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   4. Diazepam
   5. Ethyl alcohol
   6. Zafirlubast
   7. Oral rehydration solution.

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2. (a) Differentiate between typical and atypical antipsychotic agents. Mention their therapeutic use and adverse effects. 9
   (b) How is potency of an anasthetic agent assessed ? Give clinical application of thiopental and ketamine 6
3. (a) What is hypothesis of depression ? Classify antidepressants and describe their mechanism of action with associated side effects. 9
   (b) Write a brief note on drug dependence. 6
4. (a) Give the difference between partial and generalized seizures. Describe various mechanisms of action of antiepileptic drugs. 10
   

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   (b) Describe the symptoms and management of overdose of barbiturates. 5
5. Classify and elaborate the mechanism of action of nonsteroidal anti-inflammatory drugs. Add a note on Cox-II inhibitors. 15
6. (a) What is meant by clinical trials ? Explain different phases of clinical trials. 9
   (b) Explain in detail about CNS stimulants. 6
7. Justify the use of any two of the following : 15
   1. Rabeprazole in Zollinger-Ellison syndrome.

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   2. Carbidopa with levodopa in Parkinsons's disease.
   3. Salbutamol in bronchial asthma.
   4. Procain in local Anasthetics.

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