Download RTMNU B.Pharma 6th Semester 2016 Summer Pharmacology 4 Question Paper

TKN/KS/16-7001

Sixth Semester Examination for the Degree of Bachelor of Pharmacy

PHARMACOLOGY - IV

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Paper - 6 T 3

Time: Three Hours ] [Max. Marks: 80

N. B. : (1) Question no. 1 is compulsory.

(2) Solve any four questions from the remaining.

(3) Draw neat labeled diagram wherever necessary.

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(4) Discuss the reaction, mechanism wherever necessary.

(5) Assume suitable data wherever necessary.

1. Solve any five of the following :-
   1. Write mechanism of action of any two class of antifungal agents.
   2. Enlist various immunostimulants with their uses.
   3. Discuss various designs used in clinical trials.

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   4. Justify the use of Rifampicin in TB.
   5. Discuss mechanism of action of any two anthelmentic agents.
   6. Role and Responsibilities of Health professionals in management of clinical trials.
   7. Write various mechanisms of development of microbial resistence.

   4x5=20

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2. What are general principles of cancer chemotherapy. Classify anticancer agents. Discuss mode of action and adverse effects of any two classes of anticancer drugs. 15
3. 1. Explain the life cycle of malerial parasite. Discuss pharmacotherapy of malaria. 10

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   2. Write note on Antiviral agents. 5
4. 1. What is Diabetis mellitus. Justify the sale of oral hypoglycemics in treatment of type II diabetes. 10
   2. Write about antithyroid drugs. 5

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5. 1. Write a detailed account on B lactum antibiotics.
   2. Discuss about drug treatment of leprosy. 10
   3. 5
6. Explain mechanism of action, adverse effects and uses of following (any three)
   1. Pioglitazone

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   2. Ciprofloxacin
   3. Methotrexate
   4. Streptomycine
   5. Metformine.

   5x3=15

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850

7. Write short note on following (any three) :—
   1. Immunosuppressant agents.

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   2. Anabolic steroids.
   3. ICH-GCP guidelines for clinical research.
   4. Antiamoebic agents.
   5. Role of macrolides and aminoglycosides in microbial infections.

   5x3=15

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