Download RTMNU B.Pharma 6th Semester 2017 Summer Pharmaceutics 6 Question Paper

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B.Pharm. Sixth Semester (C.B.S.) Examination

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PHARMACEUTICS—VI (Physical Pharmacy)

Paper-1

Time: Three Hours]

[Maximum Marks: 80

N.B. :— (1) Question No. 1 is compulsory.

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(2) Solve any four questions from the remaining.

(3) Draw neat labelled diagram wherever necessary.

(4) Discuss the reaction, mechanism wherever necessary.

1. Solve any five : (4×5=20)
   1. What is complexation ? Give types of complexes.
   2. How does temp. affect drug stability ?

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   3. Explain glass transition with examples.
   4. Define partition coefficient. Explain the significance of it.
   5. Describe in brief various Non-Newtonian Systems.
   6. Define Diffusion. Explain in brief Fick's law of diffusion.
   7. Explain in brief about bulges and spurs.

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2. 1. Derive Scatchard Hildebrand equation. (8)
   2. Elaborate various solute solvent interactions. (7)
3. What is thixotropy ? Explain antithixotropy and rheopexy. Write in detail about measurement of thixotropy. (15)

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4. 1. Describe in detail thermal properties of polymers. (8)
   2. Discuss various pharmaceutical applications of polymers. (7)
5. 1. Explain solubility and pH titration method for determination of complexes. (8)
   2. Explain in detail steady state diffusion. (7)

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6. Explain effect of solvent and catalysis on rate of chemical reaction. (15)
7. Write short notes on (any two) : (7.5×2=15)
   1. Accelerated stability study
   2. Determination of diffusion coefficient
   3. Two component system containing liquid phases.

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