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Download RTMNU B.Pharma 7th Semester 2016 Winter Biopharmaceutics and Pharmacokinetics Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 7th Semester 2016 Winter Biopharmaceutics and Pharmacokinetics Question Paper

This post was last modified on 19 January 2020

This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University


B.Pharm. Seventh Semester (C.B.S.) Examination

BIOPHARMACEUTICS AND PHARMACOKINETICS

Paper-6 (7-T-6)

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KNT/KW/16/6581

[Full Marks : 80

N.B. :— (1) Q. No. 1 is compulsory.

(2) Attempt any four questions from remaining.

(3) Draw neat labeled diagram wherever necessary.

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(4) Discuss the reaction, mechanism wherever necessary.

(5) Use of electronic calculator, excluding programmable calculator is permitted.

  1. Solve any five : 4×5=20
    1. Enlist the factors affecting drug absorption.
    2. Give various barriers to drug distribution.
    3. Give criteria for Biowavers to bioequivalence study.
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    5. Give in-vitro dissolution testing apparatus mentioned in USP.
    6. What are the important characteristics of microsomal enzymes ?
    7. Write about Non-renal routes of drug elimination.
    8. Define Vmax and Km.
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  3. Give physiology of cell membrane. Describe in detail the mechanism of drug transport from GIT. 15
    1. Define pharmacokinetics. Give an account on one compartment open model for single oral dose administration. 8
    2. Define Absolute Bioavailability and Relative Bioavailability. Describe methods of assessing Bioavailability. 7
    1. Describe Biopharmaceutical Classification System. Give an account on theories of dissolution. 8
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    3. Discuss the factors affecting Gastric Emptying of drugs. 7
    1. Give significance of Drug-protein binding. Explain in detail why plasma albumin is considered as an important protein for drug binding. 8
    2. Give various factors affecting drug metabolism. Describe in brief Extraction Ratio and First-pass Effect. 7
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    1. Describe zero order kinetic process with suitable example. Add an account on in-vitro, in-vivo correlation. 8
    2. Describe non-oral routes of drug absorption. 7
  5. Write short notes on (any three) : 5×3=15
    1. Michaeles Menton equation.
    2. Purpose of Bioavailability testing
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    4. Pathways of metabolism
    5. Bioequivalence study.

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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University