This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
B.Pharm. Seventh Semester (C.B.S.) Examination
BIOPHARMACEUTICS AND PHARMACOKINETICS
Paper-6 (7-T-6)
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KNT/KW/16/6581
[Full Marks : 80
N.B. :— (1) Q. No. 1 is compulsory.
(2) Attempt any four questions from remaining.
(3) Draw neat labeled diagram wherever necessary.
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(4) Discuss the reaction, mechanism wherever necessary.
(5) Use of electronic calculator, excluding programmable calculator is permitted.
- Solve any five : 4×5=20
- Enlist the factors affecting drug absorption.
- Give various barriers to drug distribution.
- Give criteria for Biowavers to bioequivalence study.
- Give in-vitro dissolution testing apparatus mentioned in USP.
- What are the important characteristics of microsomal enzymes ?
- Write about Non-renal routes of drug elimination.
- Define Vmax and Km.
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- Give physiology of cell membrane. Describe in detail the mechanism of drug transport from GIT. 15
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- Define pharmacokinetics. Give an account on one compartment open model for single oral dose administration. 8
- Define Absolute Bioavailability and Relative Bioavailability. Describe methods of assessing Bioavailability. 7
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- Describe Biopharmaceutical Classification System. Give an account on theories of dissolution. 8
- Discuss the factors affecting Gastric Emptying of drugs. 7
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- Give significance of Drug-protein binding. Explain in detail why plasma albumin is considered as an important protein for drug binding. 8
- Give various factors affecting drug metabolism. Describe in brief Extraction Ratio and First-pass Effect. 7
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- Describe zero order kinetic process with suitable example. Add an account on in-vitro, in-vivo correlation. 8
- Describe non-oral routes of drug absorption. 7
- Write short notes on (any three) : 5×3=15
- Michaeles Menton equation.
- Purpose of Bioavailability testing
- Pathways of metabolism
- Bioequivalence study.
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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University