Download RTMNU B.Pharma 7th Semester 2016 Winter Pharmaceutical Medicinal Chemistry 3 Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 7th Semester 2016 Winter Pharmaceutical Medicinal Chemistry 3 Question Paper

KNT/KW/16/6577
B.Pharm. Semester?VII (C.B.S.) Examination
PHARMACEUTICAL MEDICINAL CHEMISTRY ? III
Paper ? 2
Time : Three Hours] [Full Marks : 80
NB. :? (1) Q. N0. 1 is compulsory.
(2) Attempt any F OUR questions from remaining.
(3) Draw neat labelled diagrams wherever necessary.
1. Solve any five from the following :
(a) Discuss the Biosynthesis of adrenergic neumtransmeter.
(b) Give the classification of anti arrythmic agent.
(0) What is SERM ?7 Explain in brief.
((1) What is cholinergic agent ? Explain with example.
(6) Write SAR of diuretic.
(1) State the synthesis of clonidine.
(g) What is anticoagulant ? Explain the blood coagulation pathway.
2. (a) What are female sex hormones ? Explain with classification and SAR of each category.
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(b) Write a note on oral contraceptive.
3. What is antihypertensive agent ? Explain with structure mode of action and SAR of each category.
15
4. (a) What do you mean by anticholinergic agent ? Add a note on neuromuscular blocking agents.
8
(b) Write a brief note on ganglionic blocker. 7
5. (a) What is anti-anginal agent ? Give the SAR and synthesis of anti-anginal agents. 8
(b) Add a note on cardiotonics. 7
6. What is adrenoreceptor blocker ? Give the classification and SAR of adrenoreceptor along with
synthesis of propranolol. 15
7. (a) Give detail emphasis on biosynthesis, storage, release and metabolism ofAch. 7
(b) Write the Biosynthesis pathway of testosterone and aldosterone from cholesterol. 8
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