Download RTMNU B.Pharma 7th Semester 2016 Winter Pharmaceutical Medicinal Chemistry 3 Question Paper

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B.Pharm. Semester–VII (C.B.S.) Examination

PHARMACEUTICAL MEDICINAL CHEMISTRY – III

Paper – 2

Time: Three Hours]

[Full Marks: 80

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N.B. :— (1) Q. No. 1 is compulsory.

(2) Attempt any FOUR questions from remaining.

(3) Draw neat labelled diagrams wherever necessary.

1. Solve any five from the following :

   1. Discuss the Biosynthesis of adrenergic neurotransmeter. (4)

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   2. Give the classification of anti arrythmic agent. (4)
   3. What is SERM ? Explain in brief. (4)
   4. What is cholinergic agent ? Explain with example. (4)
   5. Write SAR of diuretic. (4)
   6. State the synthesis of clonidine. (4)

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   7. What is anticoagulant ? Explain the blood coagulation pathway. (4)
2. 1. What are female sex hormones ? (8)
   2. Write a note on oral contraceptive. (7)

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3. What is antihypertensive agent ? Explain with structure mode of action and SAR of each category. (15)

4. 1. What do you mean by anticholinergic agent ? Add a note on neuromuscular blocking agents. (8)
   2. Write a brief note on ganglionic blocker. (7)

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5. 1. What is anti-anginal agent ? Give the SAR and synthesis of anti-anginal agents. (8)
   2. Add a note on cardiotonics. (7)

6. What is adrenoreceptor blocker ? Give the classification and SAR of adrenoreceptor along with synthesis of propranolol. (15)

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7. 1. Give detail emphasis on biosynthesis, storage, release and metabolism of Ach. (7)
   2. Write the Biosynthesis pathway of testosterone and aldosterone from cholesterol. (8)