Download RTMNU B.Pharma 1st Semester 2015 Winter Pharmaceutical Biochemistry Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 1st Semester 2015 Winter Pharmaceutical Biochemistry Question Paper

TKN/KS/16 ?6972
First Semester Examination For the Degree
of Bachelor of Pharmacy
PHARMACEUTICAL BIOCHEMISTRY
1T4
Time : Three Hours] [MaX. Marks : 80
N. B. :(1) Question No.1 is Compulsory.
(2) Attempt any Four questions from the remain?
ing.
(3) Draw neatlabeled diagram wherever necessary.
1. Solve any Five of the following :?
(a) Classify lipids with suitable examples. Write about
their structural features.
(b) Give the various reactions of glucose.
(0) Enlist the various factors affecting enzyme action
and explain the effect of substrate concentration
and pH on enzyme action.
(d) Define Acid value and saponification value with
its significance.
(e) Differentiate between DNA and RNA.
(1) Justify sucrose is non reducing while maltose and
lactose are reducing sugars.
(g) Write about oc?helical structure of protein.
4 x 5 = 20
2. Write a detail account of Embden?Meyerhof pathway.
Give the energetics in aerobic and anaerobic conditions.
15
TKN/KS/16 ? 6972 Contd.
5??
Define enzyme inhibition. Explain its various types
along with their therapeutic applications. 15
4. (a) Explain Transamination, Deamination and
Decarboxylation reaction of amino-acid. 10
(b) Write about galactose metabolism. 5
5. (a) Discuss the reactions of B?oxidation of fatty acids.
10
(b) Explain biosynthesis of prostaglandins. 5
6. Write a detail account of TCA cycle. Calculate the
total number of ATP utilized in TCA cycle. 15
7. Write short notes on any Three of the following :?
(a) Nucleotide and Nucleoside.
(b) Urea cycle.
(0) Phospholipid and Sphingolipid.
(d) Michaelis?Menten equation. 15
TKN/KS/16?6972 2 850